See Also: Online Research Resources
for Genetic and Genomic Researchers
for Genetic and Genomic Researchers
Online Research Resources Developed at NHGRI
NHGRI Research Projects
- Breast Cancer Information Core (BIC)
A central repository for information regarding mutations and polymorphisms in breast cancer susceptibility genes.
- Clinical Genomic Database (CGD)
A manually-curated database of all conditions with known genetic causes, focusing on the utility of genetic/genomic diagnosis and the availability of disease-specific interventions.
- Histone Sequence Database
An updated collection of histone-fold containing proteins.
- Homeodomain Resource
An annotated collection of non-redundant protein sequences, three-dimensional structures, and genomic information for the homeodomain protein family.
- Limb Morphology Database
Standardized terms used to describe human morphology developed by an international group of clinicians working in the field of dysmorphology.
- Mnemiopsis Genome Project Portal
Access to the annotated Mnemiopsis genomic sequence, the first set of publicly available whole-genome sequencing data from any ctenophore species.
- Multiplex Initiative
A large, multi-disciplinary research collaboration to examine the effects of genetic susceptibility testing for several common health conditions.
- NHGRI Dog Genome Project
A project to develop resources necessary to map and clone canine genes in an effort to utilize dogs as a model system for genetics and cancer research.
- Pallister-Hall Syndrome
Information for professionals and families caring for or affected by Pallister-Hall Syndrome.
- Pigment Cell Gene Resource
A centralized, comprehensive resource of published scientific data relevant to pigment cell biology.
- Red Cell Membrane Disorder Mutations Database
A database containing confirmed mutations to inherited disorders of the erythrocyte membrane associated with hemolytic anemia including Hereditary Spherocytosis (HS), Hereditary Elliptocytosis (HE) Hereditary Pyropoikilocytosis (HPP).
- Supplementary Material
Supplementary material not available through publishers' Web sites for NHGRI manuscripts published from 2012-present.
- Zebrafish Insertion Collection (ZInC)
A Web-based, searchable collection of zebrafish mutations generated by DNA insertion.
NHGRI-Developed Software and Analysis Tools
A Bayesian genotype caller for NextGen sequencing data.
- Conserved Domain-based Prediction (CDPred)
A computational algorithm that is designed to theoretically calculate the effect of substituting an amino acid relative to the reference sequence within functional modules - the protein domains.
A portal providing users a single, unified point-of-access to data generated by the ENCODE Pilot Project.
A data management system designed to facilitate genetic studies of complex traits.
- Genometric Analysis Simulation Program (G.A.S.P.)
A software suite that provides an interactive user interface for the mining and analysis of microarray gene expression data.
- Graphical Assessment of Sliding P-values (GrASP)
A graphical tool to present p-values from sliding-window haplotype tests of association.
A software suite for quantitative trait and locus-specific heritability estimation and association testing using the revised ROMP method.
A tool for the detection of genetic alterations in tumors from Next Generation sequence data.
A tool for scoring exonic variants for features associated with exon skipping and ectopic splice site creation.
A tool for the design and selection of overgo probes optimized for high-throughput comparative mapping.
- Tiled Regression Analysis Package (TRAP)
A software framework for selecting a set of genetic predictors which jointly explain trait variation with an additive regression model.
An annotation and analysis tool for next-generation sequencing variants in rare diseases and small pedigrees.
A graphical java program designed to display, sort, filter, and generally sift variation data from massively parallel sequencing experiments.
Last Updated: June 5, 2013