Highlights Archive

Showing all entries (from most to least recent)

Physician looking at a computer screen with genomic data (illustration). Original photo by Daniel Sone, NCI

NIH grants examine how genomic information can affect patients' health

New National Institutes of Health (NIH) grants aim to gauge if genomics can help diagnose diabetes, keep heart disease patients out of hospitals and guide cancer clinicians and patients to the most effective drugs. These pilot demonstration awards, totaling more than $11 million, are part of the Implementing Genomics in Practice (IGNITE) program administered by the National Human Genome Research Institute, part of NIH. Read more

Posted: October 23, 2014  

Ellen Rolfes

Ellen Rolfes appointed new NHGRI executive officer

Following a rigorous national search, Ellen Rolfes, M.A., has been appointed the executive officer of the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH). A human resources specialist and broadly accomplished as an administrative professional, Ms. Rolfes has worked at NHGRI for nearly two decades and at NIH for 25 years. Read more

Posted: October 20, 2014  

Screenshot from the NHGRI video

NHGRI has an exciting new video!

Check out NHGRI's exciting new showcase video! The fifteen-minute montage spotlights programs - by institute scientists and NHGRI-funded institutions - that are paving the way for the genomic revolution. The fast-paced video also highlights milestones in genomic history and the pioneers who made it happen through the use of rarely seen archival videos and photos. YouTube video Watch the video

Posted: October 19, 2014  

Eric Green and panelists at the National Museum of Natural History

Closing symposium features genomics, global health and the future

Fans of Genome: Unlocking Life's Code, an exhibition created by the NHGRI and the Smithsonian National Museum of Natural History, assembled at NMNH's Baird Auditorium on Sept. 30, for a celebratory symposium, Genomics and Global Health: What does the Future Hold? The symposium was the closing event for the exhibition and also hailed the exhibition's opening at the Reuben H. Fleet Science Center in San Diego, the first in a series of museums the exhibition is scheduled to visit. Read more
YouTube video See videos from the Smithsonian closing event

Posted: October 16, 2014  

ASHG 2014 meeting banner

NHGRI research spotlighted at ASHG 64th annual meeting

National Human Genome Research Institute researchers and trainees will contribute 11 platform presentations and more than 50 posters describing institute research at the 64th annual meeting of the American Society of Human Genetics. The highly anticipated annual meeting at the San Diego Convention Center, Oct. 18-22, will focus on human genetics and cutting-edge science across this rapidly evolving field. Read more

Posted: October 07, 2014   |  Comments (0)

Larry Brody

The Genetics of Complex Disease

On August 4, 2014, Larry Brody, Ph.D., senior investigator at NHGRI's Medical Genomics and Metabolic Genetics Branch and director of the Division of Genomics and Society, presented The Genomics of Complex Diseases for the 2014 NHGRI Summer Workshop in Genomics (Short Course). YouTube video Watch the presentation

Posted: October 06, 2014  

The Genomics Landscape
Eric Green

Laboratory-Developed Tests: Public Comments Sought

In this month's The Genomics Landscape, Dr. Green describes a recent release from the U.S. Food and Drug Administration (FDA) announcing the steps that they are taking to help ensure the reliability of certain diagnostic tests. The FDA announcement comes at a critical transition for genomic medicine. Read more


Posted: October 03, 2014  

GM7

Genomic Medicine Centers Meeting VII: Genomic Clinical Decision Support

On October 2-3, 2014, the National Human Genome Research Institute (NHGRI) sponsored the seventh Genomic Medicine Centers meeting - Genomic Medicine Centers VII: Genomic Clinical Decision Support - Developing solutions for Clinical and Research Implementation.
Read the agenda
Follow on Twitter: #GCDS2014

Posted: September 30, 2014  

Genome Advance of the Month
Colorized scanning electron micrograph of filamentous Ebola virus particles. Credit: National Institute of Allergy and Infectious Diseases, NIH

Investigating the Genomic Origins of the 2014 Ebola Outbreak

The Ebola virus in West Africa has infected and killed thousands of people in the region. Despite treatment and containment efforts, the epidemic persists with a fatality rate of 52 percent. In the August 28 online issue of Science, research scientists from Harvard University used genomic sequencing techniques to study the current outbreak's origin, transmission and relation to other outbreaks. Read more

Posted: September 30, 2014  

UDN map

DNA Sequencing Core sites selected for Undiagnosed Diseases Network

The National Institutes of Health announced today that Baylor College of Medicine, Houston, and the Medical College of Wisconsin, Milwaukee, will be providing DNA sequencing for the Undiagnosed Diseases Network (UDN). These two universities will become the DNA Sequencing Core sites for the UDN. Read more

Posted: September 29, 2014   |  Comments (0)

Video now available
Meeting room

Watch Now: September Council Open Session

Videos of the open session meeting of the seventy-second National Advisory Council for Human Genome Research, are now available. Council met September 8 and discussed the NHGRI Genome Sequencing Program, the ELSI Research Program and the ENCODE Project. YouTube video View agenda and videos

Posted: September 22, 2014  

Genome Unlocking Life's Code

Register Now: Genomics and Global Health:
What does the future hold?

A closing symposium for the Smithsonian exhibition Genome: Unlocking Life's Code, will be held on September 30th, beginning at 1 p.m. Created in partnership with NHGRI, the National Museum of Natural History, and the Foundation for the National Institutes of Health, the exhibition, and the closing symposium, Genomics and Global Health: What does the future hold?, focus on how genomics can prevent, diagnose, treat and cure diseases for individuals, their families and global populations. The event is free but registration is required. Read more

Posted: September 15, 2014  

Social network illustrated with six people connected via helix

NHGRI study uses social media to recruit

Researchers from NHGRI's Social and Behavioral Research Branch are using the power of social media and mobile phones to study what people around the world think about the intersections between genomics, genetics and society. Called the Social Genomics Project, it is comprised of seven surveys that ask questions about health risks, the flow of health information among family and friends, the use of genomic information to make important life and health decisions, as well as ancestry and race. Read more

Posted: September 15, 2014  

Microbial biofilm of mixed species from human body. From A. Earl (Broad Institute/MIT, 2012)

Researchers look more closely at the HMP's role in health and disease

As the Human Microbiome Project (HMP) comes into clearer focus, three NIH-funded research teams are gathering data at the most basic molecular levels about the biological processes that make up the host-microbiome system. The data, published in the September 10 issue of Cell Host & Microbe, highlight studies on pregnancy and preterm birth, inflammatory bowel disease and diabetes. Read more

Posted: September 10, 2014  

NIH Clinical Center

CCGO awards exome sequencing data to NIH intramural investigators

Ten intramural investigators will receive exome sequencing data for their research projects at the NIH Clnical Center as part of the Clinical Center Genomics Opportunity (CCGO). The CCGO, sponsored in part by NHGRI, is a two-year initiative encouraging NIH institutes to jumpstart genomic medicine by increasing the use of genomic data in clinical research. Read more

Posted: September 10, 2014  

Letters of A, T, C, G

NHGRI workshop offers potential paths to discovery and the clinic

On July 28-29, the National Human Genome Research Institute (NHGRI) held a workshop on the future of its flagship Genome Sequencing Program (GSP) - Future Opportunities for Genome Sequencing and Beyond: A Planning Workshop for the National Human Genome Research Institute. Workshop organizer and GSP program director, Adam Felsenfeld, Ph.D., acknowledged the many challenges ahead for NHGRI and the field of genomics - especially in the areas of clinical genomics and genetic variation associated with common diseases. Read more

Posted: September 08, 2014  

Council group photo

Advisory council to meet in open session

The seventy-second National Advisory Council for Human Genome Research will meet in open session Monday, September 8, 2014, at Fishers Lane Terrace-Level Conference Center. The Genome Sequencing Program, ELSI Research Program and ENCODE Project will be discussed. Read the agenda
Follow on Twitter at #NHGRICouncil

Posted: September 04, 2014  

The Genomics Landscape: A Message from the Director
Eric Green

The Natural Evolution of Genomic Data Sharing

Rapid and broad data sharing has been a hallmark of genomics since the early days of the Human Genome Project (HGP). Today, it is well-appreciated in genomics that the work of individual investigators and large collaborative efforts alike benefits from access to data resources. The new NIH Genomic Data Sharing Policy - released on August 27 - promotes sharing a broader array of large-scale human and non-human genomic data generated for appropriate research purposes when those data are generated through NIH-supported or NIH-conducted research. Read more

Posted: September 03, 2014  

Katherine Blizinsky and Elizabeth Tuck

NHGRI welcomes new education and policy fellows

Elizabeth Tuck, M.A., and Katherine Blizinsky, Ph.D., will begin their fellowships - sponsored by NHGRI and the American Society of Human Genetics - in September 2014. Ms. Tuck starts her fellowship in the new Genetics and Education Fellowship program, while Dr. Blizinsky starts hers in the Genetics and Public Policy Fellowship program. Read more

Posted: September 02, 2014  

Genome Advance of the Month
Mitochondrial DNA

Researchers examine disease-causing mutations in mitochondrial genomes

The study of genetic disease has often centered on the human nuclear genome. In contrast, the other genome that resides within us, the mitochondrial genome, has received less attention. July's Genome Advance of the Month features a study in the July 22 issue of Proceedings of the National Academy of Sciences, which examined disease-causing mutations in the mitochondrial genomes of otherwise healthy people. Read more

Posted: August 29, 2014  

Globe with genomic data circling around

NIH issues finalized policy on genomic data sharing

The National Institutes of Health has issued a final NIH Genomic Data Sharing (GDS) policy. GDS will promote data sharing as a way to speed the translation of data into knowledge, products and procedures that improve health while protecting the privacy of research participants.
Read the NIH Genomic Data Sharing Policy
Read the News Release

Posted: August 27, 2014  

Video now available
Elaine Mardis

Dr. Elaine Mardis on next-generation sequencing technologies

Recently, Elaine Mardis, Ph.D., Director of Technology Development for The Genome Institute at Washington University in St. Louis, presented Next-Generation Sequencing Technologies, the 14th and final lecture for the 2014 Current Topics in Genome Analysis (CTGA) series. Dr. Mardis is a preeminent leader in the field of next-generation sequencing. YouTube video View the video
Read about the 2014 CTGA series

Posted: August 18, 2014  

Video now available
Julie Segre

The Genomics of Microbes and Microbiomes

In June, Julie Segre, Ph.D., Chief, Translational and Functional Genomics Branch, presented the Current Topics in Genome Analysis lecture: Genomics of Microbes and Microbiomes. Watch the lecture here:
YouTube video View the video
Read about the full series

Posted: August 11, 2014  

The Genomics Landscape: A Message from the Director

Undiagnosed Diseases Network: Solving Medical Mysteries

The Undiagnosed Diseases Program (UDP), launched in 2008 as a partnership among NHGRI, the NIH Clinical Center and the Office of Rare Diseases Research, seeks to provide answers to patients with mysterious conditions that have eluded diagnosis. This multidisciplinary clinical and research team has diagnosed ~100 patients, discovered two previously unknown diseases and identified 50 genes not previously associated with any other human disease. Read more

Posted: August 05, 2014  

Genome Advance of the Month
Blood vein with DNA helices

Improving the detection of heart transplant rejection with DNA sequencing

With the hope of reducing the risks associated with heart transplants, scientists have been working diligently to develop a new, less invasive method to test for rejection. June's Genome Advance of the Month features research published in the June 18 issue of Science Translational Medicine that demonstrates how sequencing and quantification of cfdDNA can determine whether or not a heart transplant will be rejected. Read more

Posted: August 01, 2014  

FDA logo

FDA proposes oversight of laboratory-developed tests

The U.S. Food and Drug Administration (FDA) has announced steps to ensure that certain tests used by health care professionals to diagnose and treat patients provide accurate, consistent and reliable results. These steps come at a critical time for genomic, or precision, medicine. As more and more genetic tests are developed and marketed, the public must be confident in the accuracy and clinical validity of these tests.
Read the FDA release
Read a statement from NIH Director Francis Collins

Posted: July 31, 2014  

DNA double helix

Native peoples groups and NHGRI convene symposium on genomic research

On June 23, the National Congress of American Indians (NCAI), the National Human Genome Research Institute (NHGRI) and the National Museum of the American Indian (NMAI) convened a one-day symposium to explore perspectives surrounding Native peoples and genomic research. A Spectrum of Perspectives: Native Peoples and Genetic Research was held in association with the Smithsonian's Genome: Unlocking Life's Code. Read more

Posted: July 30, 2014  

Letters of A, T, C, G

NHGRI holds workshop on the future of the genome sequencing program

On July 28-29, genome researchers, clinicians, computational biologists and others met to consider the possible size, scope and future opportunities for the National Human Genome Research Institute's (NHGRI) Genome Sequencing Program (GSP). Future Opportunities for Genome Sequencing and Beyond: A Planning Workshop for the National Human Genome Research Institute was webcast live on July 28 and 29.
View the video presentations
Read about the workshop
Follow on Twitter at #GSPfuture

Posted: July 21, 2014  

Microbial biofilm of mixed species from human body. From A. Earl (Broad Institute/MIT, 2012)

Report for Human Microbiome Science: Vision for the Future is now available

Nearly 250 experts were convened last July for the Human Microbiome Science: Vision for the Future conference in Bethesda, Md., where scientists discussed current advances, challenges and opportunities for human microbiome research at the National Institutes of Health. A report of the meeting is now available in the journal Microbiome.
Read the summary
2013 meeting agenda, videos and slides

Posted: July 16, 2014  

Video now available
Kathleen Merikangas

Recent Advances in the Epidemiology and Genetics of Bipolar Disorder

On June 20, Kathleen Merikangas, Ph.D., chief of the Genetic Epidemiology Branch at the National Institute of Mental Health (NIMH), presented Recent Advances in the Epidemiology and Genetics of Bipolar Disorder. This final lecture in the Genomics in Medicine lecture series summarized the environmental and genetic risk factors for mood disorders, and presented advances in applying the tools of molecular genetics to bipolar disorder. Watch the lecture here: YouTube video View the video

Posted: July 14, 2014