En EspanolTalking Glossary of Genetic Terms
Leslie G. Biesecker, M.D. defines Nonsense Mutation
Nonsense Mutation
A nonsense mutation is the substitution of a single base pair that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid. The presence of this premature stop codon results in the production of a shortened, and likely nonfunctional, protein.
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