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A Catalog of Published Genome-Wide Association Studies

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The genome-wide association study (GWAS) publications listed here include only those attempting to assay at least 100,000 single nucleotide polymorphisms (SNPs) in the initial stage. Publications are organized from most to least recent date of publication, indexing from online publication if available. Studies focusing only on candidate genes were excluded from this catalog. Studies were identified through PubMed literature searches, comparisons with an existing database of GWAS literature (HuGE Navigator) and reports from the media.

SNP-trait associations listed here are limited to those with p-values < 9.5 x 10^-6 and not previously reported. Note that SNPs replicated in subsequent GWA studies are therefore not included. For most studies, only the five most significant SNPs reaching this significance level are listed. Multipliers of powers of 10 in p-values were rounded to the nearest single digit; odds ratios and allele frequencies were rounded to two decimals. Standard errors were converted to 95 percent confidence intervals where applicable. Allele frequencies, p-values, and odds ratios derived from the largest sample size, typically a combined analysis (initial plus replication studies), are recorded below if reported; otherwise statistics from the initial study sample are recorded. Odds ratios < 1 in the original paper were converted to OR > 1 for the alternate allele. ORs derived from multiple models reported in the original paper were prioritized as follows: 1) additive (per-allele) model 2) heterozygotes relative to homozygotes for the non-risk allele. P-values from 2-degree of freedom models are preferentially reported over those based on 1-degree of freedom models where both were available.

Gene regions corresponding to SNPs were identified from the UCSC Genome Browser. Genes are those reported by the authors in the original paper. Only one SNP within a gene or region of high linkage disequilibrium is recorded unless there was evidence of independent association.

How to cite this site:
Hindorff LA, Junkins HA, and Manolio TA. A Catalog of Published Genome-Wide Association Studies. Available at: www.genome.gov/26525384. Accessed [date of access].

This table is also available for download in MS-Excel format. To save the file, use an .xls extension.
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Abbreviations used on this page

For questions or comments about this page, send an e-mail to: gwas_table@mail.nih.gov

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First Author: (last name)
Disease/Trait:	(string search) or Addiction Age-related macular degeneration Aging traits Alzheimer's disease Amyotrophic lateral sclerosis APOE*e4 carriers with late onset Alzheimer's disease Asthma Atrial fibrillation Atrial fibrillation/atrial flutter Attention-deficit/hyperactivity disorder Bipolar disorder Black vs. blond hair color Black vs. red hair color Blond vs. brown hair Blood lipid traits Blood pressure Blue vs. green eyes BMI Body mass index Bone mineral density Bone mineral density (hip) Bone mineral density (spine) Breast cancer Burning and freckling C-reactive protein Celiac disease Chronic lymphocytic leukemia Cognitive test performance Colorectal cancer Coronary artery calcification Coronary disease Coronary spasm in women Crohn's disease Crohn's disease and Sarcoidosis (combined) Cutaneous basal cell carcinoma Cystatin C Diabetes related insulin traits Diabetic nephropathy Early onset extreme obesity Echocardiographic traits Electrocardiographic traits End-stage renal disease Endothelial function traits Environmental confusion in the home Episodic memory Exercise treadmill test traits Exfoliation glaucoma F-cell distribution Factor VII Fasting plasma glucose Fetal hemoglobin levels Freckles Gallstones General cognitive ability HDL cholesterol Hearing impairment Heart failure Heart rate variability traits Height Hemostatic factors and hematological phenotypes Hip bone size Hip geometry HIV1 viral setpoint Hypertension Idiopathic pulmonary fibrosis Incident diabetes Inflammatory bowel disease Iris color Irritable bowel syndrome Juvenile idiopathic arthritis Knee osteoarthritis Late onset Alzheimer's disease LDL cholesterol Lung adenocarcinoma Lung cancer Lupus Major CVD Male-pattern baldness Mean forced vital capacity from 2 exams Melanoma Memory performance Methamphetamine dependence Morbidity-free survival Multiple sclerosis Myocardial infarction Myopathy Narcolepsy Neuroblastoma Neuroticism Nicotine dependence Obesity Obesity-related traits Osteonecrosis of the jaw Other pulmonary function traits Other subclinical atherosclerosis traits Parkinson's disease Plasma level of vitamin B12 Progressive supranuclear palsy Prostate cancer Prostate cancer (aggressive) Protein quantitative trait loci Psoriasis QT interval prolongation Recombination rate (females) Recombination rate (males) Red vs. non-red hair Response to diuretic therapy Response to iloperidone treatment (PANSS-T score) Response to iloperidone treatment (QT prolongation) Response to interferon beta therapy Response to ximelagatran treatment Restless legs syndrome Rheumatoid arthritis Sarcoidosis Schizophrenia Select biomarker traits Serum IgE levels Serum urate Serum uric acid Skin pigmentation by reflectance spectroscopy Skin sensitivity to sun Sleep duration Sleepiness Smoking cessation Soluble ICAM-1 Stroke Subarachnoid aneurysmal hemorrhage Systemic lupus erythematosus Systemic lupus erythematosus in women Thyroid stimulating hormone Tonometry TP53 carriage Treatment response to TNF antagonists Triglycerides Type 1 diabetes Type 2 diabetes Type 2 diabetes and 6 quantitative traits Ulcerative colitis Urinary albumin excretion Urinary bladder cancer Volumetric brain MRI Waist circumference and related phenotypes Waist circumference traits Warfarin maintenance dose Wet age-related macular degeneration YKL-40 levels (hold Ctrl-key when selecting multiple entries)
Chromosomal Region: (e.g., "13q21.31")
Gene: (e.g., "LRP5")
SNP: (e.g., "rs20755555")
OR greater than:
p-Value threshold: Enter the exponent. For example, enter "5" for p<10-5
As of 11/13/08, this table includes 202 publications and 436 SNPs.