Segre Publications

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


Julie A. Segre, Ph.D.

Chief & Senior Investigator, Translational and Functional Genomics Branch
Head, Microbial Genomics Section

Selected Publications

Grice EA, Kong HH, Renaud G, Young AC; NISC Comparative Sequencing Program, Bouffard GG, Blakesley RW, Wolfsberg TG, Turner ML, Segre JA. A diversity profile of the human skin microbiota. Genome Res, 18(7):1043-50. 2008. [PubMed]

Grice EA, Kong HH, Conlan S, Deming CB, Davis J, Young AC; NISC Comparative Sequencing Program, Bouffard GG, Blakesley RW, Murray PR, Green ED, Turner ML, Segre JA. Topographical and temporal diversity of the human skin microbiome. Science, 324(5931):1190-2. 2009. [PubMed]

Kong HH, Segre JA. Bridging the translational research gap: a successful partnership involving a physician and a basic scientist. J Invest Dermatol, 130(6):1478-80. 2010. [PubMed]

Grice EA, Snitkin ES, Yockey LJ, Bermudez DM; NISC Comparative Sequencing Program, Liechty KW, Segre JA. Longitudinal shift in diabetic wound microbiota correlates with prolonged skin defense response. Proc Natl Acad Sci U S A, 107(33):14799-804. 2010. [PubMed]

Grice EA, Segre JA. The skin microbiome. Nat Rev Microbiol, 9(4):244-53. 2011. [PubMed]

Snitkin ES, Zelazny AM, Montero CI, Stock F, Mijares L; NISC Comparative Sequence Program, Murray PR, Segre JA. Proc Natl Acad Sci U S A, 108(33):13758-63. 2011. [PubMed]

Kong HH, Oh J, Deming C, Conlan S, Grice EA, Beatson MA, Nomicos E, Polley EC, Komarow HD, NISC Comparative Sequence Program, Murray PR, Turner ML, Segre JA. Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis. Genome Res, 22(5):850-9. 2012. [PubMed]

Grice EA, Segre JA. The Human Microbiome: Our Second Genome. Annu Rev Genomics Hum Genet, 13:151-70. 2012. [PubMed]

Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature, 486(7402):207-14. 2012. [PubMed]

Naik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, Trinchieri G, Segre JA, Belkaid Y. Compartmentalized Control of Skin Immunity by Resident Commensals. Science, 337(6098):1115-9. 2012. [PubMed]

Conlan S, Mijares LA, Comp Seq Program N, Becker J, Blakesley RR, Bouffard GG, Brooks S, Coleman HL, Gupta J, Gurson N, Park M, Schmidt B, Thomas PJ, Young A, Otto M, Kong HH, Murray PR, Segre JA. Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates. Genome Biol, 13(7):R64. 2012. [PubMed]

Snitkin ES, Zelazny AM, Thomas PJ, Stock F; NISC Comparative Sequencing Program, Henderson DK, Palmore TN, Segre JA. Tracking a Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae with Whole-Genome Sequencing. Sci Transl Med, 4(148):148ra116. 2012. [PubMed]

Conlan S, Kong HH, Segre JA. Species-Level Analysis of DNA Sequence Data from the NIH Human Microbiome Project. PLoS One, 7(10):e47075. 2012. [PubMed]

Oh J, Conlan S, Polley E, Segre JA, Kong HH. Shifts in human skin and nares microbiota of healthy children and adults.  Genome Med, 4(10):77. 2012. [PubMed]

Oh J, Segre JA. Genomics: Resident risks.  Nature, 490(7418):44-6. 2012. [PubMed]

Yang JY, Brooks S, Meyer JA, Blakesley RR, Zelazny AM, Segre JA, Snitkin ES. Pan-PCR, a computational method for designing bacterial-typing assays based on whole genome sequence data. J Clin Microbiol, 51(3):752-8. 2013. [PubMed]

Snitkin ES, Zelazny A, Gupta J, Palmore TN, Murray PR, Segre JA. Genomic insights into the fate of colistin resistance and Acinetobacter baumannii during patient treatment. Genome Res, 23(7):1155-62. 2013. [PubMed]

Findley K, Oh J, Yang J, Conlan S, Deming C, Meyer JA, Schoenfeld D, Nomicos E, Park M, NISC Comparative Sequencing Program, Kong HH, Segre JA (2013) Topographic diversity of fungal and bacterial communities in human skin. Nature, 498(7454):367-360. 2013. [PubMed]

Oh J, Freeman AF; NISC Comparative Sequencing Program, Park M, Sokolic R, Candotti F, Holland SM, Segre JA, Kong HH. The altered landscape of the human skin microbiome in patients with primary immunodeficiencies, Genome Res, 23(12):2103-14. 2013. [PubMed]

Oh J, Byrd AL, Deming C, Conlan S, NISC Comparative Sequence Program, Kong HH, Segre JA Biogeography and individuality shape the functional divergence of the human skin metagenome. Nature, 2014. [In Press].

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Last Updated: August 7, 2014