Meltzer Publications

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


Paul S. Meltzer, M.D., Ph.D.

Adjunct Investigator, Medical Genetics Branch, National Human Genome Research Institute
Senior Investigator and Chief
Genetics Branch
Center for Cancer Research, National Cancer Institute [cancer.gov]

Selected Publications

Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan X-Y, Sauter G, Kallioniemi O-P, Trent JM, Meltzer PM. AIB1, A Novel Steroid Receptor Co-activator Amplified in Breast and Ovarian Cancer. Science, 277: 965-968. 1997. [PubMed]

Khan J, Simon R, Bittner M, Chen Y, Leighton SB, Pohida T, Smith PD, Jiang Y, Gooden GC, Trent JM, Meltzer PS. Gene Expression Profiling of Alveolar Rhabdomyosarcoma with cDNA Microarrays. Cancer Res, 58: 5009-13. 1998. [PubMed]

Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS. cDNA Microarrays Detect Activation of a Myogenic Transcription Program by the PAX3-FKHR Fusion Oncogene. Proc Natl Acad Sci U S A, 96: 13264-9. 1999. [PubMed]

Bittner M, Meltzer P, Chen Y, Jiang Y, Seftor E, Hendrix M, Radmacher M, Simon R, Yakhini Z, Ben-Dor A, Sampas N, Dougherty E, Wang E, Marincola F, Gooden C, Lueders J, Glatfelter A, Pollock P, Carpten J, Gillanders E, Leja D, Dietrich K, Beaudry C, Berens M, Alberts D, Sondak V, Hayward N, Trent J. Molecular Classification of cutaneous malignant melanoma by gene expression profiling. Nature, 406: 536-540. 2000. [PubMed]

Gruvberger S, Ringner M, Chen Y, Panavally S, Saal LH, Borg A, Ferno M, Peterson C, Meltzer PS. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res, 61(16): 5979-84. 2001. [PubMed]

Khan J, Wei JS, Ringner M, Saal LH, Ladanyi M, Westermann F, Berthold F, Schwab M, Antonescu CR, Peterson C, Meltzer PS. Classification and diagnostic prediction of cancers using gene-expression profiling and artificial neural networks. Nat Med, 7(6): 673-679. 2001. [PubMed]

Allander SV, Nupponen NN, Ringner M, Hostetter G, Maher GW, Goldberger N, Chen Y, Carpten J, Elkahloun AG, Meltzer PS. Gastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile. Cancer Res, 61(24): 8624-8. 2001. [PubMed]

Allander SV, Illei PB, Chen Y, Antonescu CR, Bittner M, Ladanyi M, Meltzer PS. Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation. Am J Pathol, 161(5): 1587-95. 2002. [PubMed]

Gruvberger SK, Ringner M, Eden P, Borg A, Ferno M, Peterson C, Meltzer PS. Expression profiling to predict outcome in breast cancer: the influence of sample selection. Breast Cancer Res, (1): 23-6. 2003. [PubMed]

Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM, Moses TY, Hostetter G, Wagner U, Kakareka J, Salem G, Pohida T, Heenan P, Duray P, Kallioniemi O, Hayward NK, Trent JM, Meltzer PS. High frequency of BRAF mutations in nevi. Nat Genet, 33(1): 19-20. 2003. [PubMed]

Gruvberger-Saal S.K., Eden P., Ringner M., Baldetorp B., Chebil G., Borg A., Ferno M., Peterson C., Meltzer P.S. Predicting continuous values of prognostic markers in breast cancer from microarray gene expression profiles. Mol Cancer Ther, 3:161-168, 2004. [PubMed]

Pavey S., Johansson P., Packer L., Taylor J., Stark M., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A., O-Rourke MG, Parsons PG, Meltzer P, Ringner M, Hayward NK. Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene, 23:4060-4067. 2004. [PubMed]

Yen PM, Feng X, Flamant F, Chen Y, Walker RL, Weiss RE, Chassande O, Samarut J, Refetoff S, Meltzer PS. Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep, 4(6): 581-7. 2003. [PubMed]

Cunliffe HE, Ringner M, Bilke S, Walker RL, Cheung JM, Chen Y, Meltzer PS. The gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles. Cancer Res, 63(21): 7158-66. 2003. [PubMed]

Yu Y, Khan J, Khanna C, Helman L, Meltzer PS, Merlino G. Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Med, 10(2):175-81. 2004. [PubMed]

Weeraratna AT, Becker D, Carr KM, Duray PH, Rosenblatt KP, Yang S, Chen Y, Bittner M, Strausberg RL, Riggins GJ, Wagner U, Kallioniemi OP, Trent JM, Morin PJ, Meltzer PS. Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome. Oncogene, 23(12):2264-74. 2004. [PubMed]

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Last Reviewed: February 21, 2012