September 7, 2011: Genomics Education for Health Care Professionals in the 21st Century [JAMA]
In a recent Journal of the American Medical Association article, Genomics Education for Health Care Professionals in the 21st Century, W. Gregory Feero, M.D., Ph.D. and Eric D. Green, M.D., Ph.D., focus on how recent genomic discoveries have brought about far-reaching advances in understanding the molecular basis of human health and disease. NHGRI's vision for the future of genomics research suggests more discoveries are likely to occur over the next few decades.
March 7, 2011: Genetics/Genomics and Nursing Education [wiley.com]
To support genetic and genomic training in healthcare professional education programs, Jean Jenkins, Ph.D., R.N., F.A.A.N., National Human Genome Research Institute (NHGRI), and Kathleen Calzone, M.S.N., R.N., A.P.N.G., F.A.A.N., National Cancer Institute (NCI), have coordinated a series of articles that highlight the importance of genetics and genomics for nurse educators and nursing education worldwide. Genetics/Genomics and Nursing Education, will appear free in the Journal of Nursing Scholarship throughout 2011.
November 26, 2010:Enhancing the Feasibility of Large Cohort Studies [jama.ama-assn.org]
A recent Journal of the American Medical Association article, Enhancing the Feasibility of Large Cohort Studies by NHGRI's Teri Manolio, M.D., Ph.D. and Dr. Rory Collins at the University of Oxford, UK, focuses on the need for large cohorts to reliably assess genetic and environmental factors.
New England Journal of Medicine Series on Genomic Medicine
November 1, 2010:New England Journal of Medicine Series on Genomic Medicine
The publication of the draft sequence of the human genome in 2000 heralded the promise of incorporating genomic knowledge into patient care. Ten years later, a new series of articles, beginning with the May 27, 2010 issue of the New England Journal of Medicine, is taking a comprehensive look at what has been accomplished in the quest to screen, prevent and treat disease in the new world of genomic medicine.
March 1, 2010:Canine Morphology: Hunting for Genes and Tracking Mutations [plosbiology.org]
An essay by NHGRI Senior Investigator Elaine Ostrander, Ph.D., and co-author Abigail Shearin, a University of Pennsylvania veterinary student pursuing research in the Ostrander Lab, explore why domestic dogs vary so much in size and shape, as well as coat texture, color and patterning. The essay highlights the unique features of dog populations that offer advantages for genetic studies.
Fabio Candotti, M.D.
Senior Investigator, NHGRI
January 29, 2009:Gene Therapy Fulfilling Its Promise [nejm.org]
NHGRI Senior Investigator Fabio Candotti, M.D., of the Genetics and Molecular Biology Branch, and co-author Donald B. Kohn, M.D., Keck School of Medicine, University of Southern California, comment on prospects for continuing advancement of gene therapy for treatment of genetic diseases in light of the outcome of gene therapy for severe combined immunodeficiency disease, or SCID, due to deficiency of the enzyme adenosine deaminase (ADA), reported in recent trials.
Dr. Candotti's and Dr. Kohn's comments were based on the NEJM article: Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency [Abstract]
November 2009: The challenges of sequencing by synthesis
Today's high throughput, low cost sequencing systems have brought revolutionary advances to our ability to sequence increasing numbers of genomes for research and early clinical applications. Further improvements could further reduce cost and improve genome quality.