Giniger Publications

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


Edward Giniger, Ph.D.

Adjunct Investigator, National Human Genome Research Institute
Senior Investigator, National Institute of Neurological Disorders and Stroke [ninds.nih.gov]

Selected Publications

Giniger, E. How do Rho family GTPases direct axon growth and guidance? A proposal relating signaling pathways to growth cone mechanics. Differentiation, 70: 385-396. 2002. [PubMed]

Crowner, D., Madden, K., Goeke, S. and Giniger, E. Lola regulates midline crossing of CNS axons in Drosophila. Development, 129: 1317-1325. 2002. [PubMed]

Crowner, D., Le Gall, M., Gates, M.A. and Giniger, E. Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway. Curr Biol, 13: 967-972. 2003. [PubMed]

Goeke, S., Greene, E.A., Gates, M.A., Grant, P.K., Crowner, D., Aigaki, T. and Giniger, E. Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila. Nature Neuroscience, 6: 917-924. 2003. [PubMed]

Horiuchi, T. Giniger, E. and Aigaki, T. Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola. Genes, Dev 17: 2496-2501. 2003. [PubMed]

Le Gall, M. and Giniger, E. Identification of two binding regions for the Suppressor of Hairless protein within the intracellular domain of Drosophila Notch. J. Biol. Chem, 279: 29418-29426. 2004. [PubMed]

Connell-Crowley, L., Vo, D., Luke, L., Giniger E. Drosophila lacking the Cdk5 activator, p35, display defective axon guidance, age-dependent behavioral deficits and reduced lifespan. Mech of Dev, 124(5):341-9. 2007. [PubMed]

Spletter, M.L., Liu, J., Liu, J., Su, H., Giniger, E., Komiyama, T. Quake, S. and Luo, L. Lola regulates Drosophila olfactory projection neuron identity and targeting specificity. Neural Develop, 2: 14. 2007. [PubMed]

Le Gall, M., DeMattei, C. and Giniger, E. Molecular separation of two signaling pathways for the receptor, Notch." Dev. Biol, 313:556-567. 2008. [PubMed]

Song, J.K., Giniger, E. and Desai, C.J. The receptor tyrosine phosphatase PTP69D antagonizes Abl tyrosine kinase to guide axons in Drosophila. Mech of Dev, 125:247-256. 2008. [PubMed]

J.K. Song, R. Kannan, G. Merdes, J. Singh, M. Mlodzik and E. Giniger. Disabled is a bona fide component of the Abl signaling network. Development. 137(21):3719-27. [PubMed]

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Last Updated: March 11, 2014