HHT: Vascular Biology and Pathophysiology Workshop Future Directions

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


Hereditary Hemorrhagic Telangiectasia: Vascular Biology
and Pathophysiology

Future Directions

On the second day of the meeting, each attendee participated in a workshop subgroup focused on one of the following areas: the transforming growth factor-? pathway, vascular biology, endothelial biology, and organ pathophysiology. Each of the subgroups was asked to focus on three questions:

What are the most promising opportunities for HHT research in this area?
What are the current major obstacles to this area of research?
What are the best ways to advance this area of research?

The discussions from these workshops were then shared with, and refined by, the larger group, resulting in the following summary of future directions for HHT research.

Transforming Growth Factor-? pathway

What are the most promising opportunities for HHT research in this area?
What are the best ways to advance this area of research?

Shared tools and resources

 

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Vascular Biology

What are the most promising opportunities for HHT research in this area?
What are the current major obstacles to this area of research?
What are the best ways to advance this area of research?

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Endothelial Biology

What are the most promising opportunities for HHT research in this area?
What are the current major obstacles/needed resources in this area of research?

Appropriate EC models

What are the best ways to advance this area of research?

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Organ Pathophysiology

What are the most promising opportunities for HHT research in this area?
What are the current major obstacles to his area of research?
What are the best ways to advance this area of research?

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Last Reviewed: December 26, 2013