ENCODE Pilot Project: Comparative Sequence Analysis

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


ENCODE Pilot Project: Comparative Sequence Analysis

A component of ENCODE pilot project data production involves the generation of sequencing information from a number of different genomes in order to extract the maximum amount of information about the human genome through comparative analyses. Efforts are already underway at the NHGRI, University of British Columbia and the NIH Intramural Sequencing Center to identify, map and sequence, respectively; BAC clones for regions syntenic to the human ENCODE targets will be made in additional mammalian species. In addition to these ENCODE-directed efforts, sequence data generated through whole genome sequencing projects will be used in comparative analyses to help scientists better understand the human sequence. ENCODE Participants intend to abide by the Fort Lauderdale recommendations on "Sharing Data from Large-scale Biological Research Projects" when using unpublished sequence data in Project analyses.


Last Updated: March 7, 2012