NIH/NHGRI Challenge Grants in Health and Science Research

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


American Recovery and Reinvestment Act of 2009
NIH Challenge Grants in Health and Science Research
(RFA-OD-09-003)

National Human Genome Research Institute (NHGRI)

NIH has received new funds for Fiscal Years 2009 and 2010 as part of the American Recovery & Reinvestment Act of 2009 (Recovery Act), Pub. L. No. 111-5. The NIH has designated at least $200 million in FYs 2009-2010 for a new initiative called the NIH Challenge Grants in Health and Science Research.

This new program will support research on topic areas that address specific scientific and health research challenges in biomedical and behavioral research that would benefit from significant 2-year jumpstart funds.

The NIH has identified a range of Challenge Areas that focus on specific knowledge gaps, scientific opportunities, new technologies, data generation, or research methods that would benefit from an influx of funds to quickly advance the area in significant ways. Each NIH Institute, Center, and Office has selected specific Challenge Topics within the broad Challenge AreasPDF file related to its mission. The research in these Challenge Areas should have a high impact in biomedical or behavioral science and/or public health.

NIH anticipates funding 200 or more grants, each of up to $1 million in total costs, pending the number and quality of applications and availability of funds. In addition, Recovery Act funds allocated to NIH specifically for comparative effectiveness research (CER) may be available to support additional grants. Projects receiving these funds will need to meet this definition of CER: "a rigorous evaluation of the impact of different options that are available for treating a given medical condition for a particular set of patients. Such a study may compare similar treatments, such as competing drugs, or it may analyze very different approaches, such as surgery and drug therapy." Such research may include the development and use of clinical registries, clinical data networks, and other forms of electronic health data that can be used to generate or obtain outcomes data as they apply to CER.

The application due date is April 27, 2009.

Broad Challenge Areas and Specific Challenge Topics

Note: Those marked with an asterisk (*) are the highest priority topics; however, applicants may apply to any of the topics.

For NHGRI, the Challenge Topics are:

(01) Behavior, Behavioral Change, and Prevention

(02) Bioethics

(03) Biomarker Discovery and Validation

(04) Clinical Research

(05) Comparative Effectiveness Research (CER)

(06) Enabling Technologies

(07) Enhancing Clinical Trials

(08) Genomics

(09) Health Disparities

(10) Information Technology for Processing Health Care Data

(11) Regenerative Medicine

(12) Science

(13) Smart Biomaterials - Theranostics Technology, Engineering and Mathematics Education (STEM)

(14) Stem Cells

(15) Translational Science

For general information on NHGRI's implementation of NIH Challenge Grants, contact:

Dr. Mark Guyer
Director
NHGRI/Division of Extramural Research
National Institutes of Health
5635 Fishers Lane, Suite 4076 Bethesda, MD 20892-9306
Telephone: 301-496-7531
guyerm@exchange.nih.gov

For Financial or Grants Management questions, contact:

Ms. Cheryl Chick
NHGRI/DER/Grants Management Branch
National Institutes of Health
5635 Fishers Lane, Suite 4076
Bethesda, MD 20892-9306
Telephone: 301-435-7858
chickc@mail.nih.gov

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Last Updated: October 1, 2012