PhenX Rising

National Human Genome Research Institute

National Institutes of Health
U.S. Department of Health and Human Services


PhenX Real World Sharing and Implementation of the PhenX Toolkit (PhenX RISING)

PhenX Rising, Real-world, Implementation, and Sharing

Background

With the success of the development of the PhenX Toolkit (covers 21 research domains and includes 295 measures), NHGRI wanted to catalyze adoption of PhenX measures into ongoing genomic studies. This would allow for rapid feedback on the value of the resource including gaps in measures, ease of use, and overall usefulness for the research community. In early 2011, the Office of Population Genomics issued NOT-HG-11-001 and NOT-HG-11-009, "Notice of Availability of Administrative Supplements for the Addition of Standard Measures to Population-Based Genomic Research: The PhenX Toolkit."

Supplemental funds were provided to seven investigators to incorporate PhenX measures in a variety of epidemiological and population-based genomic studies. Although these projects span a variety of research domains, there is significant overlap in the PhenX measures selected, providing the potential for combined data analyses to address hypotheses of common interest to the group.

Study Investigators

PI/Institution Study Name NIH IC
Allison Aiello, Ph.D.,
University of Michigan
Ecologic Stressors, Post-Traumatic Stress Disorder, and Drug Use in Detroit NIDA
Robert Bilder, Ph.D., UCLA Human Translational Applications Core NIMH
Terry Jernigan, Ph.D., UCSD Creating a Pediatric Imaging-Genomics Data Resource NIDA
Catherine McCarty, Ph.D.,
Essentia Institute of Rural Health
Genome-Wide Study of Cataract and Low HDL in Personalized Medicine Research Project NHGRI
Dharambir Sanghera, Ph.D., University of Oklahoma Genome-Wide Association Scan to Identify Risk Genes for Type 2 Diabetes in Asian Indians NIDDK
Timothy Strauman, Ph.D., and
Ahmad Hariri, Ph.D., Duke University
Self-Regulation Failure: Identifying and Modifying a Risk Phenotype NIDA
Yi Zeng, Ph.D., Duke University Determinants of Healthy Longevity in China NIA


PhenX Domains Included

PhenX Domains Chart

Contacts

Erin M. Ramos, Ph.D., M.P.H.
Epidemiologist, Project Scientist

Heather A. Junkins, M.S.
Health Science Analyst

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Posted: June 25, 2012