| 8:30-9:00 a.m. | Welcome: Drs. Zerhouni, Collins, Alving and Weatherall |
| Moderator: Greg Evans |
| 9:00-9:30 a.m. | Plenary I: The Pathophysiology of Sickle Cell Disease: State of the Art - Martin Steinberg |
| 9:30-9:50 a.m. | Discussion |
| 9:50-10:20 a.m. | Break |
| 10:20-10:50 a.m. | Plenary II: Therapeutics for Sickle Cell Disease: State of the Art - Elliott Vichinsky |
| 10:50-11:10 a.m. | Discussion |
| 11:10-11:40 a.m. | Plenary III: Therapeutic Implications of Phenotypic Diversity - Orah Platt |
| 11:40-12:00 p.m. | Discussion |
| 12:00-1:00 p.m. | Lunch |
| Moderator: Karen Hofman |
| 1:00-1:30 p.m. | Plenary IV: Hemoglobin Switching - George Stamatoyannopoulos |
| 1:30-1:50 p.m. | Discussion |
| 1:50-2:20 p.m. | Plenary V: Gene Transfer - Michel Sadelain |
| 2:20-2:40 p.m. | Discussion |
| 2:40-3:00 p.m. | Break |
| 3:00-3:30 p.m. | Plenary VI: Small Molecule/Chemical Genomics Approaches - John Haley |
| 3:30-3:50 p.m. | Discussion |
| 3:50-4:20 p.m. | Plenary VII: Historical, Cultural, and Social Context of Clinical Research in Sickle Cell Disease - Vanessa Northington Gamble |
| 4:20-4:40 p.m. | Discussion |
| 4:40-5:00 p.m. | Instructions to Working Groups - Alan Guttmacher |
5:00-6:00 p.m.
| Reception
|
| 8:30-10:00 p.m. | Concurrent Working Groups- Session A - Therapeutic Implications of Phenotypic Diversity - Kwaku Ohene-Frempong
- Hemoglobin Switching - Susan Perrine
- Gene Transfer - Punam Malik
- Small Molecule/Chemical Genomics Approaches - Christopher Austin
- Historical, Cultural, and Social Context of Clinical Research - Lennette Benjamin
|
| 10:00-10:30 p.m. | Break |
| 10:30-12:00 p.m. | Concurrent Working Groups - Session A (Continued) |
| 12:00-1:00 p.m. | Lunch |
| 1:00-2:30 p.m. | Concurrent Working Groups - Session B - Therapeutic Implications of Phenotypic Diversity - Swee-Lay Thein
- Hemoglobin Switching - George Dover
- Gene Transfer - David Bodine
- Small Molecule/Chemical Genomics Approaches - Alan Schechter
- Historical, Cultural, and Social Context of Clinical Research - Joseph Telfair
|
| 2:30-3:00 p.m. | Break |
| 3:00-4:30 p.m. | Concurrent Working Groups - Session B (Continued) |
7:00-9:30 p.m.
| Group Dinner - Remarks by Sir David Weatherall
|
| Moderator: Alan Guttmacher |
| 8:00-8:30 a.m. | Presentation/Discussion - Working Groups on Therapeutic Implications of Phenotypic Diversity |
| 8:30-9:00 a.m. | Presentation/Discussion - Working Groups on Hemoglobin Switching |
| 9:00-9:30 a.m. | Presentation/Discussion - Working Groups on Gene Transfer |
| 9:30-10:00 a.m. | Presentation/Discussion - Working Groups on Small Molecule/Chemical Genomics Approaches |
| 10:00-10:30 a.m. | Break |
| 10:30-11:00 a.m. | Presentation/Discussion - Working Groups on Historical, Cultural and Social Context of Clinical Research in Sickle Cell Disease |
| 11:00-1:00 p.m. | Where to go from here - led by Drs. Weatherall and Collins |
