The Cancer Genome Atlas (TCGA)
The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. TCGA is a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), which are both part of the National Institutes of Health, U.S. Department of Health and Human Services.
Mission and Goal
The Cancer Genome Atlas will assess the feasibility of a full-scale effort to systematically explore the entire spectrum of genomic changes involved in human cancer.
The overarching goal of The Cancer Genome Atlas is to improve our ability to diagnose, treat and prevent cancer.
Video Courtesy of the National Cancer Institute.
- The Cancer Genome Atlas publishes results for bile duct, uterine and breast cancer
News Feature: May 4, 2017
- TCGA study identifies genomic features of cervical cancer [cancer.gov]
News Release: January 23, 2017
- TCGA study reveals new clues to the genomic diversity of prostate cancers
News Feature: November 5, 2015
- Peering at brain and skin cancers through a genomic lens, scientists begin to rewrite rules for identifying tumor types
News Feature: June 24, 2015
- The Cancer Genome Atlas (TCGA): The next stage [cancergenome.nih.gov]
Announcement: March 9, 2015
- NIH-funded study uncovers range of molecular alterations in head and neck cancers, new potential drug targets
News Relase: January 28, 2015
- TCGA study improves understanding of genetic drivers of thyroid cancer
Media Availability: October 23, 2014
- Rare kidney tumor provides insights on role of metabolic changes in cancer
Media Availability: August 21, 2014
- TCGA researchers identify four subtypes of stomach cancer
News Release: July 23, 2014
- Study identifies novel genomic changes in the most common type of lung cancer
News Release: July 14, 2014
- TCGA bladder cancer study reveals potential drug targets, similarities to several cancers
News Release: January 29, 2014
- As genomics breaches cancer walls, researchers forge new treatment paths
News Feature: January 13, 2014
- TCGA study of glioblastoma tumor genome reveals new details, potential treatment strategies
News Feature: October 27, 2013
- The benefits of looking across many cancer genomes: A perspective
News Feature: September 27, 2013
- Kidney cancer progression linked to shifts in tumor metabolism
News Release: June 23, 2013
- Study establishes basis for genomic classification of endometrial cancers
News Release: May 1, 2013
- TCGA researchers identify potential drug targets, markers for leukemia risk
News Release: May 1, 2013
- Study reveals genomic similarities between breast cancer and ovarian cancers
News Release: September 23, 2012
- The Cancer Genome Atlas completes detailed ovarian cancer analysis
News Release: June 29, 2011
- Researchers discover key mutation in acute myeloid leukemia
News Release: November 10, 2010
- The Cancer Genome Atlas Identifies Distinct Subtypes of Deadly Brain Cancer That May Lead to New Treatment Strategies
News Release: January 19, 2010
- President Announces Major Recovery Act Funding for The Cancer Genome Atlas Project
Presidential NIH Visit and News Release: September 30, 2009
- The Cancer Genome Atlas Reports First Results of Comprehensive Study of Brain Tumors
News Release: September 4, 2008
- The Cancer Genome Atlas Awards Funds for Technology Development
News Release: July 2, 2007
- National Institutes of Health to Map Genomic Changes of Lung, Brain, and Ovarian Cancers [cancergenome.nih.gov]
September 13, 2006
- NIH Launches Comprehensive Effort to Explore Cancer Genomics [cancergenome.nih.gov]
News Release: December 13, 2005
- The Cancer Genome Atlas
An informational brochure about The Cancer Genome Atlas
- Mapping the Cancer Genome
In the March 2007 issue of Scientific American, NHGRI Director Francis S. Collins and National Cancer Institute Deputy Director for Advanced Technologies and Strategic Partnerships Anna D. Barker find that pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies.
- Toward a Comprehensive Genomic Analysis of Cancer [cancergenome.nih.gov]
The report from a workshop co-organized by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI) as part of their collaboration to initiate the pilot phase of the Human Cancer Genome Project (HCGP), July 20-22, 2005.
- Report to the National Cancer Advisory Board [cancergenome.nih.gov]
Report from the Advanced Biomedical Technology Working Group of the National Cancer Advisory Board (NCAB), February 16, 2005.
NHGRI TCGA Program Staff
Carolyn Hutter, Ph.D.
Heidi J. Sofia, Ph.D.
Last Updated: May 31, 2018