Genomic Medicine X: Research Directions in Pharmacogenomics Implementation

On May 2-3, 2017, the National Human Genome Research Institute (NHGRI) sponsored its 10th Genomic Medicine meeting - Genomic Medicine X: Research Directions in Pharmacogenomics Implementation - at the Sheraton Silver Spring Hotel in Silver Spring, Maryland.

The objectives of the meeting were to:

Survey national landscape of research programs in pharmacogenomics implementation
Review current advances and clinical applications of pharmacogenomics
Discuss limitations and obstacles in pharmacogenomics clinical implementation
Identify evidence gaps and studies that are needed to address them
Design strategies for large-scale evaluation and implementation of pharmacogenomics in clinical care in the United States.

Meeting Summary PDF file

Executive Summary PDF file

Tweets from the meeting: #GenomicMed10 PDF file

GOLDILOKs Study: Patient Booklet PDF file

Tuesday, May 2, 2017

Time	Topic	Speaker
8:00 a.m.	Breakfast
8:30 a.m.	Welcome, Opening Remarks, General Updates	Teri Manolio NIH/NHGRI
8:45 a.m.	Announcements, Opening Remarks Video - Slides	Mary Relling (Organizing Committee Chair) St. Jude Children's Research Hospital
Session 1: The PGx Landscape - Overview of Ongoing Projects; Success Stories and Lessons Learned Moderator: Howard Jacob HudsonAlpha Institute for Biotechnology
9:00 a.m.	Angela's Story - Why Pharmacogenetics Matters Video - Slides	Guest Speaker: Paul Anderson
9:20 a.m.	Exploiting Pharmacogenetic Discovery to Improve Patient Care: Why Aren't We There Yet? Video - Slides	Keynote Speaker: Dan Roden Vanderbilt University
9:50 a.m.	NIH Supported PGx Research Video - Slides	Simona Volpi NIH/NHGRI
10:10 a.m.	Discussion on Session 1 Video
10:20 a.m.	Break
Session 2: Resources for PGx Implementation Moderator: Geoff Ginsburg Duke University
10:40 a.m.	CPIC, Clinical Pharmacogenetics Implementation Consortium and PharmGKB Video - Slides	Mary Relling St. Jude Children's Research Hospital
11:00 a.m.	ClinGen, Clinical Genome Resource and ClinVar, Clinical Variant Resource Video - Slides	Heidi Rehm ClinGen-Partners
11:20 a.m.	DiGITizE, Displaying and Integrating Genetic Information Through the EHR Video - Slides	Sandy Aronson Partners
11:40 a.m.	PharmCAT, Pharmacogenomic Clinical Annotation Tool Video - Slides	Marylyn Ritchie Geisinger Health System
12:00 p.m.	Discussion on Session 2 Video
1:00 p.m.	Working Lunch
Session 3: Implementation Research Projects Moderator: Marc Williams Geisinger Health System
1:30 p.m.	Exceptional Responders Study Video - Slides	Nikhil Wagle Dana-Farber Cancer Institute
1:50 p.m.	INdiana GENomics Implementation: an Opportunity for the UnderServed Video - Slides	Todd Skaar Indiana University
2:10 p.m.	PGx Implementation Research Programs at Northwestern Video - Slides	Minoli Perera Northwestern
2:30 p.m.	PGx Implementation at Mission Health System Video - Slides	Lynn Dressler Mission Health System
2:50 p.m.	PGx Implementation Research Programs at Vanderbilt Video - Slides	Josh Denny Vanderbilt University
3:10 p.m.	Discussion on Session 3 Video
4:10 p.m.	Break
4:30 p.m.	Panel Discussion: Research Gaps to be Addressed Dick Weinshilboum - Mayo Clinic Mary Relling - St. Jude Children's Research Hospital Micheline Piquette-Miller - University of Toronto Julie Johnson - University of Florida Steve Leeder - Children's Mercy John Wilson - Optum Video	Moderator: Rex Chisholm Northwestern University
6:00 p.m.	Meeting Adjourn

Wednesday, May 3, 2017

Time	Topic	Speaker
8:00 a.m.	Breakfast
Session 4: Evaluating Outcomes and Cost-effectiveness Moderator: Patricia Deverka American Institutes for Research
8:30 a.m.	eMERGE-PGx Video - Slides	Laura Rasmussen-Torvik Northwestern University
8:50 a.m.	Addressing Knowledge Deficits in Pediatric PGx: The GOLDILOKs Initiative at Children's Mercy Hospital Video - Slides	Steve Leeder Children's Mercy Kansas City
9:10 a.m.	Clopidogrel Video - Slides	Larisa Cavallari University of Florida
9:30 a.m.	Pragmatic Application of Economic and Cost-effectiveness Analysis: Examples from Genomic Medicine Implementation Projects Video - Slides	Marc Williams Geisinger Health System
9:50 a.m.	Discussion for Session 4 Video
10:50 a.m.	Break
Session 5: Multidisciplinary Approaches and Training PGx Practitioners Moderator: Carol Bult The Jackson Laboratory
11:10 a.m.	Multidisciplinary Approaches and Training PGx Practitioners at the University of Florida Video - Slides	Kristin Weitzel University of Florida
11:30 a.m.	The Inter-Society Coordinating Committee (ISCC) and Training PGx Practitioners Video - Slides	Robert Wildin NIH/NHGRI
11:50 a.m.	Multidisciplinary Approaches and Training PGx Practitioners at Moffitt Video - Slides	Howard McLeod Moffitt Cancer Center
12:10 p.m.	Pick up Lunch & Return to Session
12:30 p.m.	Discussion for Session 5 Video
Session 6: Role of NHGRI and the Genomic Medicine Community in PGx Implementation Research Moderator: Laura Rodriguez NIH/NHGRI
1:30 p.m.	Summary and Synthesis Video - Slides	Teri Manolio NIH/NHGRI Mary Relling St. Jude Children's Research Hospital
2:30 p.m.	Next Steps
3:00 p.m.	Meeting Adjourn

Last Updated: June 15, 2017