On-line Ed Kit
Goals of the Human Genome Project

Map and sequence the human genome

  • Build genetic and physical maps spanning the human genome.
  • Determine the sequence of the estimated 3 billion letters of human DNA, to greater than 99.99 percent accuracy.
  • Chart variations in DNA spelling among human beings.
  • Map all the human genes.
  • Begin to label the functions of genes and other parts of the genome.

Map and sequence the genomes of important model organisms,
(The approximate number of letters, or base pairs, in each species'
genome is given in parentheses.)

  • The bacterium Escherichia coli (4.6 million)
  • The yeast Saccharomyces cerevisiae (12 million)
  • The roundworm Caenorhabditis elegans (97 million)
  • The fruit fly Drosophila melanogaster (165 million)
  • The mouse Mus musculus (3 billion)
  • Other organisms (rat, zebrafish, chimpanzee, dog) will follow

Collect and distribute data

  • Distribute genomic information and the tools for using it to the research community.
    • Release within 24 hours all sequence data that spans more than 2000 base pairs.
    • Create and run databases.
    • Develop software for large-scale DNA analysis.
    • Develop tools for comparing and interpreting genomic information.
  • Share information with the wider public.

Study the ethical, legal, and social implications of genetic research

Train researchers

Develop technologies

  • Make large-scale sequencing faster and cheaper.
  • Develop technologies for finding sequence variations.
  • Develop ways to study functions of genes on a genomic scale.

Transfer technologies to the private sector










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