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Nonsense Mutation

A nonsense mutation is the substitution of a single base pair that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid. The presence of this premature stop codon results in the production of a shortened, and likely nonfunctional, protein.

Date:June 12, 2010
Credit:Darryl Leja, NHGRI
Dimensions:2279 x 1489
File Size:1.0 Mb
Rights:PublicExcept where otherwise noted, this image is in the public domain and may be used, linked or reproduced without permission. If you use an image, please credit the source listed above with a link back to www.genome.gov where possible. Thank you!



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