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2008 National DNA Day Online Chatroom Transcript

This is just one question from an archive of the National DNA Day Moderated Chat held in April 2008. The NHGRI Director and many genomics experts from across NHGRI took questions from students, teachers and the general public on topics ranging from basic genomic research, to the genetic basis of disease, to ethical questions about genetic privacy.


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Why do some animals that seem simpler that humans, such as frogs, have more genes than humans?
     Kris Wetterstrand, M.S.: Working with the Sequences, Maps and Bacterial Artificial Chromosome (BAC) Libraries Program and the ENCODE (ENCyclopedia Of DNA Elements) project. Are frogs simpler, or are they just smaller? You are basically asking about the evolution of genomes. I think this is a fascinating topic. For humans, the answer is that we may have fewer genes, but we produce multiple and different proteins from those genes.
Abbeville High School in SC (12th grade student)


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