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2008 National DNA Day Online Chatroom Transcript

This is just one question from an archive of the National DNA Day Moderated Chat held in April 2008. The NHGRI Director and many genomics experts from across NHGRI took questions from students, teachers and the general public on topics ranging from basic genomic research, to the genetic basis of disease, to ethical questions about genetic privacy.

Could there be a mutation in cells that would make a man mix with a woman?
     William Gahl, M.D.: Studying rare inborn errors of metabolism through the observation and treatment of patients in the clinic and through biochemical, molecular biological, and cell biological investigations in the laboratory. His lab focuses on a number of disorders, including cystinosis, Hermansky-Pudlak syndrome, alkaptonuria, and sialic acid diseases. Hello, It's not really a mutation that makes a man mix with a woman; it's nature itself! Some are better than others at this. You might be referring to a man who has characteristics of a woman. There are some genetic disorders in which a male (XY) can appear like a woman (XX) even though the person's cells are still XY. That can be due to a single genetic mutation.
Holy Family Catholic High School in MN (9th grade student)

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