Talking Glossary of Genetic Terms
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system. Prostate cancer generally affects men over the age of 50. It is responsible for more deaths among men than any other cancer except lung cancer.
Prostate cancer is cancer of the male reproductive tract. It is the most common cancer that exclusively affects males. It is a slow-growing cancer. In this cancer, the prostate gland grows excessively, and these cells can actually break off from the prostate gland and spread elsewhere in the body. Prostate cancer can be treated if detected early, and it is recommended that men over a certain age are screened for prostate cancer.
Name: Lawrence C. Brody, Ph.D.
Occupation: Chief & Senior Investigator, Genome Technology Branch; Head, Molecular Pathogenesis Section
Biography: Dr. Brody investigates the genetics of breast cancer and neural tube defects. As chief of the NHGRI Genome Technology Branch's Molecular Pathogenesis section, he is interested in studying genetic mutations that lead to perturbations in normal metabolic pathways and cause disorders such as cancer and birth defects. His laboratory investigates mutations in two breast cancer-linked genes, breast cancer gene 1 (BRCA1) and breast cancer gene 2 (BRCA2). Dr. Brody's laboratory was among the first to report that women carrying BRCA1 or BRCA2 mutations have a higher risk of developing both breast and ovarian cancer than women without such mutations.