Skip to main content

Division of Genomic Medicine

A Catalog of Published Genome-Wide Association Studies

Update (5/12/15): The NHGRI-EBI GWAS Catalog has moved to the European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI) at Users may now find the new search interface and updated content at this site.  Questions about the GWAS Catalog may be directed to

Why has the catalog moved to EMBL-EBI?
From September 2010 to the present, delivery and development of the Catalog has been a collaborative project between EMBL-EBI and NHGRI. In March 2015 the Catalog infrastructure moved to EMBL-EBI to enable delivery of an improved user interface, including ontology driven Catalog searching, and new curatorial infrastructure, supporting improved QC processes. Catalog content available through this original GWAS Catalog website was last updated on February 20th 2015 with all previous and updated content available at EMBL-EBI. 

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog).
Read our recent article from Nucleic Acids Research.

Published Genome-Wide Associations
Credit: Darryl Leja and Teri Manolio, NHGRI; Tony Burdett, Dani Welter, and Helen Parkinson, EBI

An archived tab-delimited file of the GWAS Catalog content prior to the EBI transition is available here: Tab Delimited File

The genome-wide association study (GWAS) publications in the Catalog include a primary GWAS analysis, defined as array-based genotyping and analysis of 100,000+ pre-QC SNPs selected to tag variation across the genome and without regard to gene content.  GWAS data from published studies which are incorporated into new GWAS analyses are eligible, provided they meet the other criteria.  Studies imputing sequencing data to genotyping arrays are eligible as long as the arrays include sufficient genome-wide coverage so that the post-imputation analysis meets the definition of a GWAS analysis, as described above. The scope of the GWAS Catalog is currently being expanded to include studies of large-scale targeted/non-genome-wide arrays, including the Metabochip, Immunochip and Exome arrays. This is currently in a pilot phase where prioritization of targeted and exome array studies for inclusion in the Catalog is by 1) relevance of the trait analyzed 2) user request.  

How to cite the NHGRI GWAS Catalog:
MacArthur J, Bowler E, Cerezo M, Gil L, Hall P, Hastings E, Junkins H, McMahon A, Milano A, Morales J, Pendlington Z, Welter D, Burdett T, Hindorff L, Flicek P, Cunningham F, and Parkinson H. The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Research, 2017, Vol. 45 (Database issue): D896-D901.

For questions or comments about this page, send an e-mail to:





Notice: The updated Catalog content may now be searched at

An archived, tab-delimited file of the GWAS Catalog content prior to the EBI transition is available here: Tab Delimited File

Date Added to Catalog (since 11/25/08) First Author/Date/ Journal/Study Disease/Trait Initial
Sample Description
Replication Sample Description Region Reported Gene(s) Mapped Gene(s) Strongest SNP-Risk Allele Context Risk Allele Frequency in Controls P-value
OR or beta-coefficient and [95% CI]
[SNPs passing QC]
11/25/08 Wilk JB
September 19, 2007
BMC Med Genet
Framingham Heart Study genome-wide association: results for pulmonary function measures.
Mean forced vital capacity from 2 exams Up to 1,222 individuals NA 7q21.3 COL1A2 COL1A2 rs441051-? intron NR 2 x 10-6 (meanFVC) NR Affymetrix
4q25 Intergenic VN1R23P - RAC1P5 rs10516541-? NR 4 x 10-6 (meanFVC) NR
11/25/08 " Pulmonary function Up to 1,222 individuals NA 15q11.2 SNRPN SNRPN rs3867498-? intron NR 1 x 10-6 (FEV1slope) NR Affymetrix
21q22.3 ADARB1 ADARB1 rs2838815-? intron NR 3 x 10-6 (meanratio) NR
15q26.1 FLJ32831 C15orf32 - LINC00930 rs1455782-? NR 4 x 10-6 (ppFVC) NR
2q36.3 RHBDD1 RHBDD1 rs3820928-? intron NR 5 x 10-6 (ppFEV1) NR
8q11.21 SNTG1 SNTG1 rs310558-? intron NR 5 x 10-6 (ppratio) NR
14q22.1 NID2 NID2 rs730532-? intron NR 6 x 10-6 (ppFEF) NR
14q23.1 Intergenic SLC35F4 - C14orf37 rs808225-? NR 7 x 10-6 (ppfefrat) NR
1q21.3 IL6R IL6R rs4129267-? intron NR 7 x 10-6 (ppFEF) NR
17p12 CDRT4 TEKT3 - CDRT4 rs2906966-? NR 8 x 10-6 (ppFEV1) NR
7q33 Intergenic RPS17P12 - IMPDH1P3 rs357394-? NR 9 x 10-6 (ppFVC) NR

Top of page

Catalog Data Last Updated: February 20, 2015
Web Page Text Last Updated: September 16, 2015