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The National Human Genome Research Institute conducts genetic and genomic research, funds genetic and genomic research and promotes that research to advance genomics in health care.


Doctor with patients in Africa

Forging a genomics research path across Africa

In 2010, the National Institutes of Health Common Fund and the United Kingdom's Wellcome Trust, in partnership with the African Society of Human Genetics, introduced the Human Heredity and Health in Africa (H3Africa) program to support African scientists conducting research on the genetic and environment factors of diseases. Five years after the program's first grants were awarded, researchers are building collaborative research networks and making discoveries about genetics and human health.

Group of people holding letters of U, D, N

Undiagnosed Diseases Network sticks around

The Undiagnosed Diseases Network, an NIH Common Fund program aimed at solving challenging medical mysteries, isn't going anywhere anytime soon. The program has just approved funding through 2022. With this investment, the UDN will continue to accept participants with undiagnosed conditions and hopes to better understand how to become self-sustaining in the future. Funding announcements are planned for Summer 2017, pending available funds.

Prostate cancer

NHGRI researchers discover new genetic variants that increase prostate cancer risk

About half of a man's risk for developing prostate cancer arises from malfunctioning genetic variants that are inherited. Finding those variants is challenging, in part because each variant makes a modest contribution to disease risk. By examining the whole exomes - the 1-2 percent of the genome containing protein-coding genes - of 75 high-risk families, NHGRI researchers identified three new variants that increase a man's risk for developing prostate cancer. The findings were published Nov. 26 in Oncotarget.

ADHD and the Brain Connectome

NIH researchers identify inherited brain connections linked to ADHD

NHGRI researchers have identified connections in the brain that are linked to Attention Deficit Hyperactivity Disorder (ADHD). Researchers studied large, multi-generational families to detect which brain connections are heritable in ADHD, those passed down from parent to child. These heritable brain features can help researchers discover and understand the genes associated with ADHD. The study was published November 16 in JAMA Psychiatry.

Expanding the ELSI Universe

Researchers in the ethical, legal and social implications (ELSI) of genomics to gather about future directions

On June 5-7, 2017, the conference Genomics and Society - Expanding the ELSI Universe will gather ethical, legal and social implications researchers to reflect on current research and discuss future directions. Submit an abstract or proposal by December 1, 2016. More information at