Perspective: Precision medicine may move us beyond the use of race in prescribing drugs

167 new molecular entities (NMEs) approved by the FDA Between 2008 and 2013. 35 of the NMEs (21%) reported some racial or ethnic differences in pharmacokinetics, safety, efficacy or pharmacogenomics. Health care providers have long struggled with considering race when prescribing and dosing medications. In a May 26 New England Journal of Medicine perspective, Vence L. Bonham, J.D., an investigator with NHGRI's Social and Behavioral Research Branch, and his colleagues, are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall. Read more

A Quarter Century after the Human Genome Project's Launch presents: Dr. David Bentley

David Bentley On Thursday, May 26th, the NHGRI History of Genomics Program will complete its six-part seminar series featuring scientists who helped launch the Human Genome Project. David Bentley, D.Phil., Illumina's vice president and chief scientist of DNA sequencing, will be the featured speaker. Dr. Bentley was a driving force behind the Sanger Centre's immense contributions to the Human Genome Project, prior to joining Illumina.
Read more about the series
Read about Dr. David Bentley

Genome: Unlocking Life's Code heads southwest

Logo for Genome: Unlocking Life's Code It's on the move again. On May 21, Genome: Unlocking Life's Code, NHGRI's genomics exhibit, created in partnership with the Smithsonian's National Museum of Natural History, is headed to the Natural History Museum of Utah in Salt Lake City. Now traveling on a five-year, multi-city tour, the exhibit challenges visitors to explore the fascinating world of genome science through high-tech, hands-on learning. For a limited time only! See it there before Sept. 5! Read more

Mouse models of Zika in pregnancy show how fetuses become infected

Mosquito A new mouse model of Zika virus infection in pregnancy is offering clues about how the virus works. Researchers at Washington University School of Medicine in St. Louis showed that the virus migrated from the pregnant mouse's bloodstream into the placenta, eventually infecting, and causing cell death, in the brains of the unborn pups. Using this mouse model, researchers hope to learn about the virus' biology and develop new vaccines and treatments. The research, co-funded by NHGRI, appears in Cell. Read the research | Read the press release

The Genomics Landscape

The Center for Inherited Disease Research at Twenty

Eric Green For this issue of The Genomics Landscape, I am delighted to feature the Center for Inherited Disease Research, which was founded in 1996. This month's issue also highlights the USA Science and Engineering festival, the Undiagnosed Diseases Network, a new online atlas of human malformation syndromes in diverse populations, and a recent virtual scientific meeting.
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