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News Release
NHGRI researchers collaborated with physicians and medical geneticists worldwide to create the Atlas of Human Malformation Syndromes in Diverse Populations.
… and descriptions of people with the same condition and ancestry. … Previously, the only available diagnostic atlas featured photos of patients with northern European ancestry, which often does not represent the characteristics … in Africa. "We found ourselves struggling to diagnose the African children," Dr. Kruszka said. "We were doing our best …
News
To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.
… more accurately assess disease risk regardless of genetic ancestry. … To prevent an emerging genomic technology from … the scores often heavily overrepresent people of European ancestry. “Recently, more and more studies incorporate multi-ancestry genomic data into the development of polygenic risk …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of Southern California** … Schaid Polygenic Risk of Disease in Populations of Diverse Ancestry UNC-Chapel Hill Yun Li*, Alexander Reiner, Nancy Cox … Across the Life-Span in Populations of Diverse Ancestry University of California, Los Angeles Bogdan …
News Release
Researchers identified 13 gene regions that influence cholesterol levels, some of which affected people differently if they are smokers or former smokers.
… (a fat or fat-like substance in the blood) in people of African ancestry. The researchers investigated whether smoking … participants in the study's first stage, 23,753 were of African descent. Of the 253,467 total participants in the …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
… on PBS’s “ Finding Your Roots .” This series explores the ancestry of people from diverse backgrounds, taking viewers … data usage and sharing policies that are specific for the African research context. NHGRI plans to participate in the … the development of genomics research capacity on the African continent. … In November 2019, the American College …
Staff
Dr. Meeks is a Research Fellow at the Center for Research on Genomics and Global Health.
… (Windhoek, Namibia) and the UNICEF Eastern and Southern African Regional Office. Before transitioning to Research … diseases in underrepresented populations, in particular African-ancestry populations. These innovative designs include …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… complex and intertwined relationships between a person's ancestry, ethnicity, and racial identity. So, we ask, is … cancer screenings, tried and true forensic techniques, DTC ancestry sleuthing, and COVID-19 tracking: all ways genomics … stories passed down through generations to taking genetic ancestry tests, we are compelled to know more about our …
Staff
Dr. Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… of diversity among genomic studies, with populations of African ancestry being particularly underrepresented, despite … in children, and is found more often among populations of African- or Hispanic ancestries. Children with COEH are …
Event
On December 7, 2022, NHGRI will host a webinar to discuss key findings from the Human Genetics and Genomics Workforce Survey Report.
… as U.S. citizens (73.3%) and their race, ethnicity or ancestry as white (67%). The top three primary areas of work … workforce demographics, which include race, ethnicity, ancestry; age; gender identity; sexual orientation; …
Staff
Dr. Guanjie Chen is a senior research fellow with the NHGRI's Center for Research on Genomics and Global Health.
… association study of hypertension and blood pressure in African Americans. PLoS Genet 2009 Jul. PMID: 19609347 … among obesity, inflammation, and Insulin Resistance in African Americans and West Africans. Obesity. 2010 Mar. PMID: … AP, Chen G, et al. Variation in APOL1 Contributes to Ancestry Level Differences in HDLc-Kidney Function …