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Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… DNA Sequencing … DNA sequencing is a laboratory technique used to determine the … understanding the function of genes and other parts of the genome. There are now several different methods available for …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… researchers use a variety of tools to compare the complete genome sequences of different species. By carefully comparing … of years - is an important step toward understanding the genome itself. It pinpoints genes that are essential to life … biology of living things have changed over time. As DNA sequencing technology becomes more powerful and less …
Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… DNA sequencing determines the order of the four chemical building … which most DNA sequencing experiments are done. The human genome contains about 3 billion base pairs that spell out the … a human being. … Since the completion of the Human Genome Project, technological improvements and automation …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… Vision — Generating and analyzing a complete human genome sequence will be routine for any research laboratory, … 92nd meeting of the National Advisory Council for Human Genome Research will take place on February 22-23. As usual, … the 1980s discussing the desirability and feasibility of sequencing the human genome, to the U.S. Department of …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… and the field of genomics. … The NIH Intramural Sequencing Center (NISC) sits on the top floor of a research … essentially unchanged in >20 years: provide contemporary genome-sequencing capabilities for intramural researchers at … to that mission, regularly generating large amounts of genome-sequence data and analyses for numerous NHGRI and NIH …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… Why was it so difficult to fully complete the human genome sequence? The Human Genome Project ended in 2003, but genomic researchers had not … with a vision. Even with new technologies, genome sequencing is still tough, time-consuming work that requires …
News Release
NHGRI will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases.
… … The National Institutes of Health will fund a set of genome sequencing and analysis centers whose research will focus on … of common and rare human diseases. … The National Human Genome Research Institute (NHGRI), part of NIH, today …
Research Funding
GS-IT provides sequence analysis tools and software to scientists who rely on genomics in their research.
… … Overview … Grantees … Program Staff … Related Content … Genome Sequencing Informatics Tools (GS-IT) provides "researcher … in their biological, biomedical and clinical research. … Genome Sequencing Informatics Tools … Genome Sequencing …
The Genomics Landscape
In the July 2019 edition of The Genomics Landscape, NHGRI Director Eric Green reflects on the milestones of the Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT) Program as it reaches completion.
… updates and monitor the ‘Genomics2020’ calendar . … The Genome: Unlocking Life's Code exhibition is currently … of Child Health and Human Development (NICHD), the Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT) … and opportunities associated with the possible use of genome sequence information in the care of newborns. …
The Genomics Landscape
In the October 2019 edition of The Genomics Landscape, NHGRI Director Eric Green focuses on recent efforts to make the human genome reference sequence useful to basic and clinical researchers and how increasing the representation of human genomic variation will remain key components of NHGRI’s Human Genome Reference Program.
… updates and monitor the ‘Genomics2020’ calendar . … The Genome: Unlocking Life's Code exhibition is currently … the field of genomics. … Research studies that generate genome-sequence data rely on a reference sequence for making … were difficult to “read out” completely using the DNA-sequencing methods available at that time. In addition, the …