Search Results
Research at NHGRI
The Immersive Simulation Program (ISP) provides expertise, tools, and support for the integration of emerging technology-based methods into health and medical research.
… to expand capabilities for innovative research including method and measure development. This work builds …
Educational Resources
Ancestry-informative markers are sets of polymorphisms for a DNA sequence found in different frequencies between populations from different geographical regions.
Educational Resources
Epigenetics is an emerging field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism.
MINC
Anticipating obstacles and challenges can help you plan strategies and methods for addressing them before they cause you a bottleneck in your progress.
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… E. coli). … Cloning, Bacteria, Bioengineering, DNA Sequencing, Base Pair, Chromosomes … A bacterial artificial … E. coli). BACs are often used in connection with DNA sequencing. Segments of an organism's DNA, ranging from … the BAC DNA, which can then be isolated and used in sequencing DNA. … A bacterial artificial chromosome (BAC) is …
Outreach
The Genome: Unlocking Life's Code exhibition celebrates the 10th anniversary of the initial sequencing of the human genome.
… exhibition celebrates the 10th anniversary of the initial sequencing of the human genome. ​ … Human Genome Sequencing, Smithsonian Exhibition, Genomics 101, Genomics … exhibition celebrates the 10th anniversary of the initial sequencing of the human genome. … Outreach …
News Release
NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about the migration of humans to the area.
… and guard humans as they have for hundreds of years. By sequencing the whole genome of a Fonni's Dog and comparing it … the migration of humans to the area. ​ … Sardinian dog sequencing, human migration, Fonni's Dogs, Sardinian's …
News Release
North Asians may be more closely related to Eastern and Northern Europeans than previously thought.
… Mongolian ancestry.  The principal component statistical method was used to map the relationships between different … This includes a number of coordinated large scale sequencing projects such as the HapMap and 1000 Genomes … previously thought. … genetic diversity, ancestry, genome sequencing, Lawrence Brody … North Asians may be more closely …
News Release
Researchers developed a technique that will aid in a more accurate reconstruction of human genomes.
… databases than are currently available. … The Trio Binning Method Genome assembly computationally reconstructs a genome from the much smaller pieces of DNA that sequencing machines are able to read, much like putting … Trio binning takes advantage of the newest generation of sequencing technology that can "read" much longer areas of …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… demonstrated in mice that gene therapy may be the best method for correcting the single faulty gene that causes … researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes … researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes …