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The Genomics Landscape
In the November 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 25th anniversary of NHGRI's Intramural Research Program.
… disease genes, including those implicated in cancer, diabetes, premature aging, hereditary deafness, and various … Map of the Genome Gene Mutation Points to New Way to Fight Diabetes, Obesity, Heart Disease Study Identifies Gene that …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… in African Americans. J Endocrinol Metab. 2012 Apr 1;2(2):51-65. Chen G, Yuan A, Zhou Y, Bentley AR, Zhou J, Chen … with obesity in West Africans and African Americans. Diabetes. 2010 Jun;59(6):1549-54. doi: 10.2337/db09- 1252. … Rotimi C. Genome-wide search for susceptibility genes to type 2 diabetes in West Africans: potential role of …
Research Funding
The Multi-Omics for Health and Disease Consortium aims to advance the application of multi-omic technologies to study health and disease in ancestrally diverse populations.
… Chicago Multi-Omics at the Intersections of Environment, Diabetes, and Kidney Disease: A Multi-Omics for Health and … include 1) persons from ancestrally diverse populations; 2) persons with and without specific diseases; 3) harmonized …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… of complex genetic diseases include heart disease, diabetes, and cancer. … A complex disease is caused by the …
Talking Glossary
Una enfermedad (o afección) compleja, cuando se analiza en el contexto de la genética, refleja un trastorno que se produce por las contribuciones de múltiples variantes genómicas y genes además de influencias considerables del entorno físico y social.
… of complex genetic diseases include heart disease, diabetes, and cancer. … Una enfermedad (o afección) compleja, …
Staff
Dr. Charles Rotimi is the scientific director of and NIH Distinguished Investigator in the Division of Intramural Research. He also serves as the director of the Center for Research on Genomics and Global Health (CRGGH).
… and blood pressure in African Americans and for type-2 diabetes in West Africans. His lab contributes to the global …
Staff
Dr. Ayo Doumatey is a Research Fellow and Laboratory Manager at NHGRI's Center for Research on Genomics and Global Health.
… Adeyemo AA, Tekola-Ayele F, Doumatey AP, et al. Impact of Type 2 Diabetes on Impaired Kidney Function in Sub-Saharan African …
News Release
NIH researchers identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood.
… of variants of the same gene in patients with a similar type of blood vessel inflammation. … The NIH group first … ability to produce of an enzyme called adenosine deaminase 2 (ADA2). Without it, abnormalities and inflammation in blood … National Cancer Institute; and the National Institute of Diabetes and Digestive and Kidney Diseases, as well as the …
Fact Sheet
Viruses are bundles of genetic material wrapped in a protein coat that can infect living things.
… Coronavirus disease 2019 (COVID-19)  Viral agent: SARS-CoV-2  … Viruses are tiny infectious particles that are halfway … white blood cells, called B cells, produces a particular type of protein called an antibody. Antibodies bind to … factors . People with existing health conditions, such as diabetes, cardiovascular disease or cancer, are more …
News Release
NHGRI hosted two Pathway to Independance awardees and supported 18 additional investigators at institutions nationwide.
… Ph.D., received his award from the National Institute of Diabetes and Digestive and Kidney Disorders, enabling him to … in the non-coding portion of the genome, with a focus on Type 2 diabetes. He is looking forward to integrating his twin …