Search Results
Policy Issues
Most genetic tests today are not regulated, meaning that they go to market without any independent analysis to verify the claims of the seller.
… Regulation Of Genetic Tests, Genetic Testing, 23andMe, Ancestry, Health Information From Genetic Testing … Most …
Clinical Research
This study evaluates patients with inherited metabolic disorders and related medical complications.
… Disorder, Inherited Disorder, Family Health History, Ancestry, Genetic Disease, Clinical Study, Genetics Study … …
15 Ways Genomics Influences Our World
Advances in genomics are helping you access information about your genome from your home.
… of such DTC genomic testing is for revealing family ancestry or genealogy [see Human Origins and Ancestry ]. For example, the company Ancestry.com started as a place to search historical and …
Staff
Lindsey Criswell, who became the director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases in February, 2021 is also an associate investigator in NHGRI's Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch.
… complex (MHC), biological pathways, genetic ancestry, epigenetic factors … Lindsey Criswell, who became …
Educational Resources
Sickle cell disease is a hereditary disease seen most often among people of African ancestry.
… hereditary disease seen most often among people of African ancestry. … Autosome, Birth Defect, Gene, Inherited, … hereditary disease seen most often among people of African ancestry. Caused by mutations in one of the genes that encode …
About Genomics
Appropriate use of population descriptors in scientific research is critical for the advancement of genomic science and human health for all.
… benefits, and challenges in using race, ethnicity, ancestry, and other population descriptors in genomics … Read the Report: Use of Race, Ethnicity, and Ancestry as Population Descriptors in Genomics Research … of population descriptors, their relation to genetic ancestry, their use in society throughout the last few …
News
To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.
… more accurately assess disease risk regardless of genetic ancestry. … To prevent an emerging genomic technology from … the scores often heavily overrepresent people of European ancestry. “Recently, more and more studies incorporate multi-ancestry genomic data into the development of polygenic risk …
News Release
In an article published in the American Journal of Human Genetics, researchers have found that words scientists use to describe populations have changed from 1949 to 2018.
… reveals that use of the term “race” has declined, while “ancestry” and “ethnicity” have increased. … National … use to describe human populations — such as race, ancestry, and ethnicity — significantly changed from 1949 to … when paired with “ethnicity.” In addition, the use of “ancestry” and “ethnicity” also has increased. The survey, …
Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.
… population descriptors — race, ethnicity and genetic ancestry — which are often used to distinguish groups of … on the distinctions between race, ethnicity and genetic ancestry, and to advance the use of population descriptors in … ethnicity are not valid or reliable proxies for genetic ancestry. In addition, genetic ancestry is a poor proxy for …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of Southern California** … Schaid Polygenic Risk of Disease in Populations of Diverse Ancestry UNC-Chapel Hill Yun Li*, Alexander Reiner, Nancy Cox … Across the Life-Span in Populations of Diverse Ancestry University of California, Los Angeles Bogdan …