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News Release
An international team of researchers including NIH has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa.
… to medical conditions in people of sub-Saharan African ancestry, and indicates that the migration from Africa in the … conducted that include populations with mainly European ancestry." The GWAS approach involves rapidly scanning … the few studies that have been conducted among African-ancestry populations have used less efficient genotyping …
Staff
Dr. Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… among genomic studies, with populations of African ancestry being particularly underrepresented, despite … using transcriptomics and genomics to describe the genetic ancestry and variation within African genomes and using the … exome sequencing reveals uncaptured variation and distinct ancestry in the Southern African population of Botswana. Am J …
News Release
20 papers published online in 2014 highlight research on DNA biorepositories and electronic medical records to better understand the genomics of disease.
… data from more than 5,000 samples of children of European ancestry from the EMRs of two large universities. The …
Media Advisory
On December 7, 2022, the National Human Genome Research Institute will host a webinar to discuss the key findings from a recently released Human Genetics & Genomics Workforce Survey Report.
… workforce demographics, which include race, ethnicity, ancestry; age; gender identity; sexual orientation; … as U.S. citizens (73.3%) and their race, ethnicity or ancestry as white (67%). The top three primary areas of work …
News Release
NHGRI researchers and colleagues are calling for health disparities research that focuses on the microbiome.
… cultural and behavioral factors in people of diverse ancestry, according to the perspective. "We hope that …
Genetic Disorders
Familial Mediterranean Fever is an inherited disease, characterized by recurrent attacks of fever, inflammation, painful, swollen joints, and ankle rash.
… of them are very common in the patients of Middle Eastern ancestry. … In making a diagnosis of Familial Mediterranean … a positive family history in people of Middle Eastern ancestry. The results of genetic testing. Also helpful in … establishing a correct diagnosis of FMF is the patient's ancestry. Testing for the following can also be helpful: …
Staff
Dr. Amy Bentley is a Staff Scientist with the NHGRI's Center for Research on Genomics and Global Health.
… traits, particularly serum lipids, in African ancestry populations. She also focuses on the complex … consortium, in order to support the inclusion of African ancestry populations in such efforts. Dr. Bentley is very … A, Rotimi CN. Phenotypic variance explained by local ancestry in admixed African Americans. Front Genet , 2015 …
The Genomics Landscape
In April 6, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how NHGRI will hold a symposium on National DNA Day, April 25, highlighting relevant and interesting topics in genomics and concluding with the annual Louise M. Slaughter National DNA Day Lecture.
… sampled over 300 dogs to characterize their genetic ancestry and found large, complex families of dogs living in …
Research Funding
ClinGen will advance genomics in clinical care and improve our understanding of phenotypic and functional effects of genetic variants and their clinical value.
… efforts in the establishment of standards in the use of ancestry and diversity information in clinical genomics and … could be prevented or mitigated if the risk were known Ancestry and Diversity Alice Popejoy Carlos Bustamante Investigate how ancestry information is used in clinical genomics and provide …
Event
On October 25-29, 2022, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.
… Traits Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Research Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … p.m. Statistical Genetics and Genetic Epidemiology Local Ancestry at the MHC region id asscociated with disease …