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News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… method. Modeled on a defense mechanism evolved by bacteria against viruses, CRISPR/Cas9 activity was first …
News Release
NIH researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children.
… Inflammation is the body's natural response to invading bacteria or viruses. The body releases chemicals that cause …
Fact Sheets
La genómica comparada es un campo de la investigación biológica en el que los investigadores usan una variedad de herramientas para comparar las secuencias del genoma completo de distintas especies. ​
… globo, la mosca de la fruta, la ascidia, la ascáride y la bacteria Escherichia coli. En el caso de algunos organismos, …
Educational Resources
A lymphocyte is a type of white blood cell that is part of the immune system.
… cells produce antibodies that are used to attack invading bacteria, viruses, and toxins. The T cells destroy the body's …
News Release
Principal investigator-mentors guide new scientists to their next chapter.
… housekeepers, are responsible for destroying foreign bacteria inside white blood cells as well as breakdown …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… genomes are much smaller compared to the genomes of most bacteria and microorganisms. Scientists  showed that it was …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… point of view, inflammation helps us survive. From the bacteria's point of view, inflammation is something to be …
15 Ways Genomics Influences Our World
Genomics is empowering farmers to improve the food supply.
… Service , and state health departments to identify bacteria that might cause outbreaks from food contamination. …
Genetic Disorders
Trimethylaminuria is a metabolic condition in which an individual is not able to convert trimethylamine into a compound called trimethylamine N-oxide.
… Taking low doses of antibiotics to reduce the amount of bacteria in the gut. This suppresses the production of …
Staff
Dr. Heidi Sofia served as a program director in the Division of Genomic Medicine at the National Human Genome Research Institute from 2010-2023.
… transcriptional responses to diverse stress signals in bacteria. Molecular Cell , 27: 793-805. 2007. [ PubMed ] …