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Educational Resources
An oncogene is a mutated gene that contributes to the development of a cancer.
… is a mutated gene that contributes to the development of a cancer. … Carcinogen, Mutagen, Cancer, Cell, Mutation, Tumor Suppressor Gene … An oncogene is a mutated gene that has the potential to cause cancer. Before an oncogene becomes mutated, it is called a …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) … how the body signals the lack of oxygen in melanoma skin cancer, National Institutes of Health (NIH) researchers … acts as a sensor for oxygen and nutrients in many types of cancer. They discovered 40 new genes that are either turned …
Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… analyze and interpret DNA sequence information from cancer patients. They have developed an algorithm that sorts … to their clinical and biological relevance to a patient's cancer. … The findings eventually may help guide … Human Genome Research Institute (NHGRI), and the National Cancer Institute, both part of the National Institutes of …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted … an association between AAV and the occurrence of liver cancer. The present research addresses this problem in gene … documented a 50-70 percent higher occurrence of liver cancer in AAV-treated mice compared with a 10 percent liver …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Steven Benowitz … Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number of new … about the biology and development of a rare form of kidney cancer. … They found that the disease - chromophobe renal … of the 66 ChRCC tumors studied, a high number for a rare cancer. The study revealed increased numbers of mitochondria …
Staff
Dr. Heidi Parker is an Associate Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch, NHGRI.
… Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch at the … laboratory of Dr. Elaine Ostrander at the Fred Hutchinson Cancer Research Center, established the first classification … genomic loci involved in complex morphological traits and cancer susceptibility. Dr. Parker has capitalized on the …
… Cáncer de próstata … Prostate cancer is a disease characterized by uncontrolled cell growth … which is part of the male reproductive system. Prostate cancer generally affects men over the age of 50. It is responsible for more deaths among men than any other cancer except lung cancer. …
Genetic Disorders
Klinefelter syndrome is a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility.
… syndrome is associated with an increased risk for breast cancer, a rare tumor called extragonadal germ cell tumor, … Syndrome, Extra X Chromosome, Infertility, Gynecomastia, Breast Cancer, Extragonadal Germ Cell Tumor, Lung Disease, …
Talking Glossary
Un carcinógeno es una sustancia, organismo o agente capaz de causar cáncer.
… is a substance, organism or agent capable of causing cancer. Carcinogens may occur naturally in the environment …
Talking Glossary
BRCA1 y BRCA2 son los dos primeros genes que se identificaron como asociados a tipos hereditarios del cáncer de mama y de ovario. Las personas con mutaciones en BRCA1 o BRCA2 tienen un riesgo mucho más alto de desarrollar cáncer de mama, de ovario u otros tipos de cáncer en comparación con las personas que no tienen mutaciones en estos genes.
… two genes found to be associated with inherited forms of breast cancer and ovarian cancer. People with mutations in either … BRCA1 or BRCA2 have a much higher risk for developing breast, ovarian or other types of cancer than those without …