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News Release
NHGRI researchers have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.
… history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. Since 2012, Laura Koehly, … family trees associated with heart disease, diabetes, breast cancer and colorectal cancer. Definitions of each …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
… the field of genomics.  …  After more than a decade, The Cancer Genome Atlas (TCGA) program is drawing to an end. A … initiated and supported by NHGRI and the National Cancer Institute (NCI), with over $300 million in total … mission to catalog the genomic changes underlying multiple cancer types. Ambitious in scope from the beginning, TCGA was …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National … Genome Atlas publishes results for bile duct, uterine and breast cancer  (2017)  TCGA study identifies genomic … risk  (2013)  Study reveals genomic similarities between breast cancer and ovarian cancers  (2012)  The Cancer Genome …
Staff
Dr. Lawrence Brody is a senior investigator in NHGRI's Social and Behavioral Research Branch and director of NHGRI's Division of Genomics and Society.
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… in normal metabolic pathways and cause disorders such as cancer and birth defects. His laboratory focuses on … a disease; variants of this type, such as those in known breast cancer-linked genes, are of great medical importance. … or BRCA2 mutations have a higher risk of developing both breast and ovarian cancer than women without such mutations. …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… switch from a different genetic neighborhood, turning on a cancer-growth gene. The research team was led by Bradley E. … in energy production, seemed to have no relevance to cancer. Dr. Bernstein and his colleagues found that when the IDH gene was mutated, particular portions of the cancer cells' DNA became studded with chemical tags called …
Staff
Dr. Bell is a senior investigator at the National Human Genome Research Institute's Cancer Genetics and Comparative Genomics Branch.
… She conducted her postdoctoral training at Fox Chase Cancer Center, Philadelphia, before joining Harvard Medical … on the fine-mapping of genomic deletions in ovarian cancer and in malignant mesothelioma as a means to home in on … the dramatic clinical responses of non-small cell lung cancer patients to gefitinib, a small molecule inhibitor of …
Staff
Elaine Ostrander is chief of NHGRI's Cancer Genetics and Comparative Genomics Branch.
… is Chief and Distinguished Senior Investigator of the Cancer Genetics and Comparative Genomics Branch at the … revealing epidemiologic features of woman at risk for breast or ovarian cancer. Dr. Ostrander’s lab is best known, … CA, Francisco LV, Ostrander EA. BRCA1 mutations and breast cancer in the general population: Analyses in women …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify … of the most clinically aggressive forms of endometrial cancer. Our research entails the functional annotation of …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify … of the most clinically aggressive forms of endometrial cancer. Our research entails the functional annotation of …
Educational Resources
A carcinogen is an agent with the capacity to cause cancer in humans.
… … A carcinogen is an agent with the capacity to cause cancer in humans. … Cancer, Tumor, Genetic Mutation, Chemical … A carcinogen is a substance, organism or agent capable of causing cancer. Carcinogens may occur naturally in the environment …