Search Results
FAQ
Questions and answers from the September 26, 2022, Multi-Omics for Health and Disease Consortium Pre-Application Webinar.
… both tumor and normal tissues from participants with cancer are strongly encouraged and will be prioritized for … setting this up could take some time. … Biosamples For the cancer DSS, can we propose just plasma collection and no … Collection of tumor samples from participants with cancer is encouraged but it is not a strict requirement. See …
Clinical Research
A study for patients with unexpected genetic results
… unexpected genetic test results about their risk for cancer, heart disease, and other conditions after having … treated or prevented. Many of these results are related to cancer risk and heart conditions . If you think you have … or Spanish  Received a genetic testing result related to cancer risk or heart disease even though they were not …
Fact Sheets
A DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes.
… cause as many as 60 percent of all cases of hereditary breast and ovarian cancers. But there is not one specific … individuals with a particular mutation actually develop breast cancer, or to identify the changes in gene sequences that are …
For Health Professionals
Essential genomics competencies, practice guidelines, and curricular resources for a variety of health professions.
… providers learning basic genetic and genomic concepts. Cancer: Breast cancer risk assessment in an African American female: Grace Male breast cancer risk analysis in a Caucasian male: Jeff with …
News Release
Research studies are now using polygenic risk scores to determine a person’s inherited risk for certain diseases, but there are inconsistencies in how these scores are calculated. NHGRI has published guidelines in Nature for how these scores should be reported.
… diseases like Type 2 diabetes, coronary heart disease and breast cancer, which involves calculating a polygenic risk score . … and co-senior author of the paper. "For diseases such as breast cancer and many others, we will be able to responsibly …
News Release
A study published NIH researchers revealed that about half of individuals who said they don’t want to receive secondary genomic findings changed their mind after their healthcare provider gave them more detailed information.
… variants that are associated with a heightened risk for breast cancer. Based on the American College of Medical Genetics and … BRCA2 , both of which are linked to an increased risk of breast and ovarian cancer. All 59 genes are associated with …
Careers and Training
NHGRI provides funding to support the development and implementation of modules aimed at providing healthcare professionals with genomic medicine training.
… of ACT sheets for select high risk PRS diseases (Breast Cancer, Heart Disease, Diabetes) that can be adapted to … variants we currently use clinically for diseases such as breast cancer, colon cancer, and coronary artery disease. …
Profile
NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
… with a specific health condition such diabetes and cancer. The study was conducted by the research group headed … genomic risks for a variety of health conditions, such as breast cancer, obesity and heart diseases. Although such risk …
File
… the best models, lessons from diverse complex diseases: Breast Cancer …
Policy Issues
Payers such as insurance companies and Medicare need systematic ways of evaluating genetic tests for reimbursement.
… tests to predict, prevent and treat disease. Tests for breast cancer and for hereditary forms of colorectal cancer can assess disease risk and guide screening and …