Search Results
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… Jeannine Mjoseth … How well cancer patients fare after chemotherapy can be affected by their social interaction with … little more likely to survive for five years or more after chemotherapy if they interacted during chemotherapy with other patients who also survived for five …
Health FAQ
Discuss these questions with your doctor or health care provider.
… going through gene therapy. The main risks are from the chemotherapy that is needed for the conditioning phase of … therapy or the gene therapy itself.   The risks from the chemotherapy include infertility, hair loss and mouth ulcers. Chemotherapy also leads to fewer white blood cells , which …
For Patients and Families
​Pharmacogenomics combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.​
… (FDA) also recommends genetic testing before giving the chemotherapy drug mercaptopurine (Purinethol) to patients … irinotecan (Camptosar), which is part of a combination chemotherapy regimen. The reasoning is that patients with one … of pharmacogenomic research. Studies have found that the chemotherapy drugs, gefitinib (Iressa) and erlotinib …
News Release
20 papers published online in 2014 highlight research on DNA biorepositories and electronic medical records to better understand the genomics of disease.
…  Genes that increase negative side effects of certain chemotherapy drugs. Hakon Hakonarson, M.D., Ph.D., director … (TPMT). TPMT metabolizes thiopurines, a class of chemotherapy drugs. In certain individuals with "loss of … variants, the body's bone marrow may be suppressed after chemotherapy treatment - a potentially severe side effect of …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… tested this hypothesis by adding 5-Azacytidine, a chemotherapy drug that disrupts formation of methyl tags, to … rarely turned on. This exciting discovery indicates that chemotherapy drugs like 5-Azacytidine may be useful for … gliomas. Nature, 529.7584:110-114. 2016. [ Nature ] … Chemotherapy May Be A Useful Treatment … Related Content … …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… mass, and tenderness or enlargement of breast tissue. Chemotherapy is usually reserved for prostate cancer recurrence or advanced disease. Chemotherapy can help to keep the disease stable and stop …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… bladder cancer include surgery and radiation combined with chemotherapy. There are no recognized second-line therapies - … cancer from patients who had not yet been treated with chemotherapy, radiation or any type of therapy. The …
Policy Issues
Payers such as insurance companies and Medicare need systematic ways of evaluating genetic tests for reimbursement.
… and preventive measures. Other tests can predict optimal chemotherapy regimens, or predict the likelihood of drug …
Event
The 2020 - 2022 Class of ISCC-PEG Scholars provided virtual presentations of the genomics education projects in which they were involved during their two years of participation in the program. Their ISCC-PEG Mentors provided introductions.
… 1:30 p.m. Utilizing Germline Pharmacogenomics to Optimize Chemotherapy Katherine Robinson, Pharm.D. Clinical …
News Release
NIH will fund researchers to develop computational approaches to figure out which differences in DNA make people more susceptible to disease.
… which genetic variants affect patient response to two chemotherapy drugs, paclitaxel and clofarabine. Stanford …