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News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… Americans and others of African ancestry carry a genomic variant that increases their risk of obesity, a finding that … person's risk of developing diabetes, hypertension, heart disease and some cancers. While obesity mostly results from … of NHGRI's Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch and director of the Center for …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… with the four themes below. The social context of genomic discovery We approach research with a social genomics lens. … social processes, behavior, and environment to affect disease processes and outcomes. We use advanced and … creating disparities in risk, morbidity, and mortality of disease. In doing so, we consider the effect of adverse …
News Release
NIH researchers have identified a treatment that significantly decreases the risk of stroke in children with a rare genetic disease called Deficiency of Adenosine Deaminase Type 2 (DADA2).
… the risk of stroke  in children with a rare genetic disease called DADA2 (deficiency of adenosine deaminase type … , and a group in Israel, independently discovered the gene variant that causes the disease using a genomic technique … around the world with fevers and unexplained strokes. The discovery that all of these children are deficient in the …
Educational Resources
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases.
… Expression, Gene Variation, Personalized Medicine, Gene Variant … A genome-wide association study (abbreviated GWAS) … that are statistically associated with a risk for a disease or a particular trait. The method involves surveying … that occur more frequently in those with a specific disease or trait compared to those without the disease or …
News Release
NHGRI researchers have successfully used facial recognition software to diagnose a rare, genetic disease in known as DiGeorge syndrome.
… facial recognition software to diagnose a rare, genetic disease in Africans, Asians and Latin Americans. … The disease, 22q11.2 deletion syndrome , also known as DiGeorge … from 1 in 3,000 to 1 in 6,000 children. Because the disease results in multiple defects throughout the body, …
Educational Resources
Polymorphism involves one of two or more variants of a particular DNA sequence.
… related to genomics, refers to the presence of two or more variant forms of a specific DNA sequence that can occur among …
News Release
UDN expands the footprint of the network with a new metabolomics core and increased model organism capabilities.
… to use that knowledge to reduce the burden of neurological disease. About the National Institutes of Health (NIH): NIH, …
Event
On June 17-18, 2021, NHGRI hosts a workshop, Multi-Omics in Health and Disease: Current Applications, Challenges and Future Directions.
… the Stage - Application of multi-omics to study health and disease Moderator: Judy Cho, Icahn School of Medicine at Mt. … 1: Multi-omics Integration to Understand Health and Disease Nancy Cox, Vanderbilt University 2:15 - 2:45 p.m. … With Multi-omics Data to Provide Insights Into Prodromal Disease and Prevention Nathan Price, Onegevity and Institute …
Educational Resources
Sickle cell disease is a hereditary disease seen most often among people of African ancestry.
… Sickle Cell Disease … Sickle cell disease is a hereditary disease seen most often among people of African ancestry. … …
The Genomics Landscape
In the July 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 10th anniversary of the Undiagnosed Diseases Program.
… to direct the program today. With the goal of improving disease management for individual patients and advancing … basic researchers to identify the underlying mechanisms of disease. Training clinicians in the use of contemporary … New Evidence that Viruses May Play a Role in Alzheimer's Disease Novel Drug Therapy Partially Restores Hearing in Mice …