Search Results
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… new smoking-related cancer subtypes and potential new drug targets, and found numerous genomic similarities with … of the National Institutes of Health. The U.S. Food and Drug Administration-approved HPV vaccines should be able to … The investigators also discovered new clues about drug resistance in head and neck cancers. They found that …
For Patients and Families
Neglected diseases are conditions that inflict severe health burdens on the world's poorest people.
… on the world's poorest people and are often overlooked by drug developers or by others instrumental in drug access. … Neglected diseases are conditions that inflict … are said to be neglected if they are often overlooked by drug developers or by others instrumental in drug access, …
News Release
The U.S. Food and Drug Administration has approved the first treatment for progeria, a rare and fatal pediatric disease, characterized by dramatic, rapid aging beginning in childhood.
… rare, fatal pediatric disease. … What The U.S. Food and Drug Administration has approved the first treatment for … of a mouse model, and the demonstration that this drug class could provide benefit. Progeria, also known as … FDA-approved treatment for progeria … The U.S. Food and Drug Administration has approved the first treatment for …
Staff
Dr. Randy Chandler is an associate investigator in the Organic Acid Research Section of the Metabolic Medicine Branch in NHGRI.
… of clinical trial start-ups by using the same gene delivery system and manufacturing methods for multiple rare … testing various gene therapy approaches, such as AAV gene delivery, genome editing, and mRNA therapy, to cure rare … to establish long-term efficacy for AAV-mediated gene delivery for MMA and PA. In addition, his research has shown …
Staff
Dr. Julie Segre is chief and a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
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… tools to track hospital-acquired infections of multi-drug resistant organisms, including the NIH's recent … reconstructed a polymicrobial outbreak of multi-drug resistant Acinetobacter baumannii that swept through the … overall fitness. MGS's long-term goal is to create a drug strategy that capitalizes on the bacterium's loss of …
Staff
Dr. Rongling Li is an epidemiologist and program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
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… medical records, gene-environment interactions, gene-drug interactions … Dr. Rongling Li is an epidemiologist and …
15 Ways Genomics Influences Our World
Advances in genomics are helping you access information about your genome from your home.
… you are interested in been approved by  the U.S. Food and Drug Administration (FDA) if it is about your health? How … Limitations To DTC Genomic Testing, Regulations, Food And Drug Administration (FDA) … Advances in genomics are helping …
Research Training
A fellowship that will prepare fellows to use genetic, genomic and pharmacogenomic approaches to advance minority health and health equity.
… Genome Research Institute (NIH NHGRI) and the Food and Drug Administration’s Office of Minority Health and Health … medical product development processes that facilitate the delivery of drugs, biologics, and devices from bench to … working closely with mentors at both FDA OMHHE, Center for Drug Evaluation and Research (CDER) and NIH NHGRI, providing …
Genetic Disorders
Cystic fibrosis is a genetic disease that causes the body to produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas.
… CF. Researchers modified a common cold virus to act as a delivery vehicle - or "vector"- carrying the normal genes to … lung. Subsequent studies have tested other methods of gene delivery, such as fat capsules, synthetic vectors, nose drops … the airways of lungs. Researchers are now testing aerosol delivery using nebulizers. But finding the best delivery …
Event
On April 10-11, the National Human Genome Research Institute (NHGRI) will sponsor a workshop titled Defining a Clinical Data Ecosystem for Genomic Health in Washington, DC.
… for optimizing genomic data integration and utilization in delivery of healthcare … Objectives … On April 10-11, the … large-scale utilization of genomic sequence data in delivery of genomic healthcare and examine research that …