Search Results
Genetic Disorders
Huntington's disease is an inherited neurological illness causing involuntary movements, severe emotional disturbance and cognitive decline.
… from generation to generation. Clinical trials of drugs: Drug testing includes classes of drugs that control symptoms, … found an effective way to slow or prevent the disease. The drug used by UC Irvine researchers to prevent the cell death … cancer in humans. This could speed up human trials of the drug in Huntington's disease patients. … The discovery of the …
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… authorized for use in the United States by the Food and Drug Administration (FDA) are mRNA vaccines. … Fact Sheet … …
Clinical Research
This study evaluates patients with inherited metabolic disorders and related medical complications.
… R. J. and Venditti, C. P. Adenovirus-mediated gene delivery rescues a neonatal lethal murine model of mut(0) …
Genetic Disorders
Wilson disease is a rare genetic condition that causes a person's body to store too much of the mineral copper, leading to organ damage that may cause death.
15 Ways Genomics Influences Our World
Genomics is helping us choose the right medication at the right dose for each patient.
… more people. That's why at this time, the U.S. Food and Drug Administration (FDA) labeling for tamoxifen does not … Resources: The Mayo Clinic - Pharmacogenomics: The Right Drug, for the Right Patient, at the Right Dose Mount Sinai … Pharmacogenomics Implementation Consortium (CPIC®) - Gene/Drug Clinical Practice Guidelines PharmGKB: Knowledge Base on …
News Release
NIH researchers have identified and tested a molecule that shows promise as a possible treatment for Gaucher disease and Parkinson's disease.
… between identifying this molecule and having an approved drug." Dr. Sidransky has conducted research on Gaucher … down cellular waste. In a process known as high-throughput drug screening, researchers at NCATS Chemical Genomics Center … see if it might be developed into an appropriate prototype drug for patients with Gaucher disease and Parkinson's …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… alterations in head and neck cancers, new potential drug targets  (2015)  TCGA study improves understanding of … r  (2014)  TCGA bladder cancer study reveals potential drug targets, similarities to several cancers r  (2014)  As … cancers  (2013)  TCGA researchers identify potential drug targets, markers for leukemia risk  (2013)  Study …
For Patients and Families
A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United States at any given time.
… for the vast majority of rare diseases. The Orphan Drug Act of 1983 provides incentives for drug companies to develop treatments for rare diseases. In … the Act was signed into federal law, the U.S. Food and Drug Administration (FDA) has approved more than 340 …
MINC
Each clinical setting is unique. Strategies that will work in your environment can be used to design your interventions based on suggested options from the Champions.
… utilization of genomic information in nursing healthcare delivery are recommended. Because assets and needs are so …
Healthcare Provider Genomics Education Resource
Genomics plays a role in every area of nursing, whether nurses are at the bedside providing one-on-one care, treating entire populations, teaching the next generation of nurses, or making discoveries in the lab.
… competency: Apply quality improvement principles in delivery of genomics nursing care.  Courses in which this …