Search Results

1 - 10 of 67
Educational Resources
Epigenetics is an emerging field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism.
… the degrees to which genes are turned on and off. Certain epigenetic modifications may be passed on from parent cell to … or from one generation to the next. The collection of all epigenetic changes in a genome is called an epigenome. … …
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… Prabarna Ganguly, Ph.D. … Comparing epigenetic differences between humans and domestic dogs … to study the aging process. By comparing when and what epigenetic changes mark certain developmental periods in … the DNA sequence itself. Recent findings have shown that epigenetic changes are linked to specific stages of aging and …
Research at NHGRI
The Translational and Functional Genomics Branch explores the genetic, epigenetic and metagenomic basis of human disorders.
… function contribute to health by exploring the genetic, epigenetic and metagenomic basis of human disorders. … TFGB … and Functional Genomics Branch explores the genetic, epigenetic and metagenomic basis of human disorders. ​ … The … and Functional Genomics Branch explores the genetic, epigenetic and metagenomic basis of human disorders. … …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… Section's research objectives is to understand the epigenetic changes that accompany red cell differentiation, including how the erythroid epigenetic profiles differ from the profiles in cells from … all functional elements in the human genome, including epigenetic marks and sites occupied by transcription factors, …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… One of these roads involves how the cell reads the epigenetic code, the "other genetic code" that sits atop a … chemical groups - like flags on the DNA - that make up the epigenetic code and act as guideposts. These flags help the … of cancer and the location, but also the molecular and epigenetic signatures of the patient's specific cancer. With …
Educational Resources
The term epigenome is derived from the Greek word epi which literally means "above" the genome.
… do it, and when to do it. Different cells have different epigenetic marks. These epigenetic marks, which are not part of the DNA itself, can …
Staff
Jennifer Strasburger was the lead Genomic Program Administrator (GPA) for NHGRI as well as the co-chair for the NHGRI Data Access Committee (DAC).
… Strasburger, Data Access Committee (DAC), informatics, epigenetic, epitranscriptomics … Jennifer Strasburger was the …
Staff
Lindsey Criswell, who became the director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases in February, 2021 is also an associate investigator in NHGRI's Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch.
… complex (MHC), biological pathways, genetic ancestry, epigenetic factors … Lindsey Criswell, who became the …
Event
The Advances in Genomic Technology Development (AGTD) 2022 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) from July 12-14, 2022 at The Jackson Laboratory (Farmington, CT).
… in situ Method to Study the Combinatorial Code of Epigenetic Marks in Single Cells Yanbo Chen Yale University … discussed genomic technologies that include nanopore and epigenetic sequencing as well as multi-omic analyses of …
15 Ways Genomics Influences Our World
We are learning how our genomes serve as blueprints for life.