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Research Funding
The centers study in innovative ways to address important ethical, legal, and social issues related to advances in genomics.
… and evolving ELSI issues is critical. All of these factors contribute to a need for new and more innovative … risks associated with genomic information, examining factors that influence how people perceive such risks. The … center conducted research on the ethical, legal and social factors that influence the translation of genetic information …
Staff
Dr. Philip Shaw is an investigator in the Social and Behavioral Research Branch at the National Human Genome Research Institute.
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… His main interest is in the genetic and environmental factors that influence the development of brain and behavior. … examines the interplay of genomic and environmental factors in shaping the developmental trajectories of brain … S, Hansen N, Elnitski, L & Shaw P. Neuroanatomic, epigenetic, and genetic differences in monozygotic twins …
15 Ways Genomics Influences Our World
We are learning how our genomes serve as blueprints for life.
Educational Resources
In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene.
… itself. Instead, gene expression is silenced by the epigenetic addition of chemical tags to the DNA during egg or sperm formation. Epigenetic tags on imprinted genes usually stay in place for …
Profile
Dr. Joan Bailey-Wilson, who retired in September 2022, looks back on her 42-year career as a scientist and reflects on the rapid growth of the genomics field.
… if you accounted for smoking and known environmental risk factors, there was still increased familial risk, which was … methods that would allow us to include environmental risk factors in our genetic analyses. Since then, we've identified … contributed to these cancers, rather than environmental factors or by chance. The group quickly embraced new …
For Teachers
The Your Genome & You infographic introduces the basics of genetics and genomics, and how the science impacts our lives.
… by demonstrating the outcome of an environmentally induced epigenetic change through animation. … Toolkit … Resources … …
Health
A polygenic risk score is one way by which people can learn what their risk of developing a disease is, based on the total number of genomics variants related to the disease.
… many of their genes, frequently coupled with environmental factors. Researchers are studying these changes to understand … that are influenced by multiple genes and environmental factors. Many diseases fall on a spectrum between these two …
About Genomics
Resources for understanding the first complete, gapless sequence of a human genome.
… 376. Doi: 10.1126/science.abj6987 (2022) Gershman et al. Epigenetic patterns in a complete human genome . Science … al. From telomere to telomere: The transcriptional and epigenetic state of human repeat elements . Science  376. … (2022) Altemose et al. Complete genomic and epigenetic maps of human centromeres . Science 376. Doi: …
About Genomics
Resources for understanding the first truly complete sequence of the Y chromosome, the final human chromosome to be fully sequenced.
… genetic features with implications for fertility, such as factors in sperm production. Learn more about this … human #YChromosome sequence! This sequence reveals genetic factors with implications for fertility. …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… the transactions between the genome and regulatory factors, such as proteins and noncoding RNAs from single … (US). Complex relationships between genetics and social factors influence health outcomes. Approximately 33% of … Probe design, image analysis, modeling, and integration of epigenetic data  Training, resources, and opportunities for …