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Educational Resources
A birth defect is an abnormality present at birth.
… in a baby at birth. Birth defects can be caused by genetic factors, prenatal events during pregnancy or a combination of …
Clinical Research
In the late 90’s and early 2000’s, scientists at the NIH highlighted an increased incidence of Parkinson disease among patients with GD and their families.
File
… Regulatory and Epigenetic Landscapes of Mammalian Genomes_031616.pdf …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… how these pieces work normally and identifying the factors that disrupt normal function is a central challenge …
Staff
Elaine Ostrander is chief of NHGRI's Cancer Genetics and Comparative Genomics Branch.
… variation, breed structure and development, and risk factors for breed-specific canine cancers. As such, the … due to sample size limitations and locus heterogeneity; factors the Ostrander lab argues can often be overcome in … 38 , 39 , 40 , 41 , 42 . Our collaborative studies of epigenetic profiling identified novel prognostic biomarkers …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… give information about your ancestry, kinship, lifestyle factors and potential disease risk. … Forensic testing is … genes. On top of that, lifestyle and environmental factors play a critical role in your development and health. …
Staff
Cynthia Tifft, M.D., Ph.D. is the deputy clinical director for the National Human Genome Research Institute.
… Medicine Christopher Morgan, Ph.D. — Associate Director of Epigenetic Research, University of Maryland School of …
Research Funding
The Genome Technology Program is refining current technologies to increase efficiency and decrease cost while maintaining or improving data quality.
… of nucleic acid sequence and genotyping along with epigenetic, functional, and synthetic genomics experiments. …
News Release
Mothers may be able to reduce guilt over their children's inherited obesity guilt by being more careful in the future about their children's diet.
… providers who discuss genomics and behavioral risk factors with overweight mothers may make those mothers feel … mechanisms are far from understood, and the genetic risk factors are complex. They include gene-gene interactions, … that people may not realize the extent to which genetic factors could influence metabolism, as well as the behavioral …
For Patients and Families
A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United States at any given time.
… genetics are just one piece of the puzzle. Environmental factors, such as diet, smoking, or exposure to chemicals, also can play a role in rare diseases. Such factors may directly cause disease, or interact with genetic factors to cause or increase the severity of disease. … …