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News Release
Researchers have discovered that FGF21 is elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia.
Event
On March 12-16, 2024, the National Human Genome Research Institute (NHGRI) will participate in the 2024 ACMG Annual Clinical Genetics Meeting - an annual medical and scientific conference continues to provide groundbreaking research and the latest advances in medical genetics, genomics and personalized medicine.
Event
On November 16-17, 2023, the National Human Genome Institute will co-sponsor a workshop, Advances in the Genetic Architecture of Complex Human Traits, to take a historically grounded and forward-looking approach towards dissecting the genetic architecture of complex traits in humans.
… environmental variation, including societal and structural factors, influencing diseases and traits? What does this mean … be used to better delineate how genetic and non-genetic factors contribute to health- and disease-related trait …
Event
On January 11, 2021, NHGRI and The George Washington University organized an interactive webinar.
… differences in illness? What social and biological factors are important? What is it like participating in a …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… research. His recent studies investigate the genetic and epigenetic basis of cancers in adult and pediatric patients, …
Educational Resources
A phenotype is an individual's observable traits, such as height, eye color, and blood type.
… by both their genomic makeup (genotype) and environmental factors. … A phenotype is an individual's observable traits, …
National Advisory Council for Human Genome Research
The Director's Report-Related Documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in May 2022.
… Nurk – The Complete Sequence of a Human Genome Gershman – Epigenetic Patterns in a Complete Human Genome Vollger – … Hoyt – From Telomere to Telomere: The Transcriptional and Epigenetic State of Human Repeat Elements Aganezov – A … of Human Genetic Variation Altemose – Complete Genomic and Epigenetic Maps of Human Centromeres Green – Completing the …
Educational Resources
Susceptibility is a condition of the body that increases the likelihood that the individual will develop a particular disease.
… influenced by a combination of genetic and environmental factors. … Susceptibility is a condition of the body that …
Fact Sheet
Diversity among genomics research participants is essential for improving the health of everyone.
…  Genomes from distinct populations differ due to multiple factors, including who people decide to reproduce with, as … that helped them adapt to environmental changes.  Factors displayed in the graphic include: reproduction, …
Staff
Dr. Sudre is an Associate Investigator in Dr. Philip Shaw's Neurobehavioral Clinical Research within the Social and Behavioral Research Branch
… G*, Chen*, Y. C., Sharp, W, et al. (2018). Neuroanatomic, epigenetic and genetic differences in monozygotic twins …