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Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, Bioengineering, DNA Sequencing, Base Pair, Chromosomes … A bacterial …
Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense … Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the …
Educational Resources
Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA Sequencing, Genome, Human Genome Project … Shotgun …
Educational Resources
A mutagen is a chemical or physical phenomenon, such as ionizing radiation, that promotes errors in DNA replication.
… such as ionizing radiation, that promotes errors in DNA replication. … Mutagen, DNA Mutation, DNA Replication, Cancer … A mutagen is a chemical or physical …
Educational Resources
Chromatin is a substance within a chromosome consisting of DNA and protein.
… Chromatin is a substance within a chromosome consisting of DNA and protein. … Chromosome, Histones, Gene Expression, DNA … Chromatin refers to a mixture of DNA and proteins that form the chromosomes found in the cells …
Educational Resources
A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.”
… Base Pair … A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.” … Genetic Code, Nucleotides, Amino Acids, … Cytosine, Guanine, Thymine, Base Pairs, Double Helix, DNA … A base pair consists of two complementary DNA …
Event
NHGRI workshop seeking scientific perspectives for relating genomic variation to human phenotype.
… NHGRI Staff 8:15 - 9:00 a.m. Current State of the Art: Functional Data, Analysis and Interpretation Hugo Bellen Lea … capabilities do we need to generate and make use of functional data? What is needed to overcome barriers to … and characterization of all genes and regulatory elements Co-Chairs: Kelly Frazer Wendy Chung Breakout 5 ( …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
… (CBFb and RUNX1, respectively) that form a dimer for DNA binding and gene expression regulation, are frequent … Current and future efforts in Dr. Liu's lab include more functional studies of CBFβ-SMMHC with novel transgenic mouse … in the zebrafish, this finding demonstrated significant functional conservation between mammalian and zebrafish …
Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… Plasmid … A plasmid is a small, often circular DNA molecule found in bacteria and other cells. … Bacteria, Chromosome, Deoxyribonucleic Acid (DNA), Gene, Cloning, DNA Sequencing, Genetic Engineering Recombinant DNA (rDNA) … …