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News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… of our genes and genome … The Encyclopedia of DNA Elements (ENCODE) Project is a worldwide effort to understand … helps to locate regions in the DNA that are “candidate functional elements” – DNA regions that are predicted to be functional elements based on these biochemical properties. …
News Release
The newly launched Impact of Genomic Variation on Function (IGVF) consortium to include 30 U.S. sites.
… function. The IGVF consortium includes five components: Functional Characterization Centers, Regulatory Network …
Staff
Dr. Laura Elnitski is a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
… look at multi-species comparisons of noncoding regulatory elements. She was awarded a Ruth L. Kirschstein National … and chicken, as well as the ENCODE Consortium to elucidate functional elements in the human genome. Her work specializes … tools to identify and discern the mechanistic action of functional elements in the human genome, including promoters, …
News Release
NIH expands its Encyclopedia of DNA Elements Project, which is creating a fundamental genomics resource scientists to study human health and disease.
… of Health (NIH) plans to expand its Encyclopedia of DNA Elements (ENCODE) Project, which is generating a fundamental … to develop and apply methods for mapping candidate functional elements in the genome, and to analyze the … which will study the biological role that candidate functional elements may play, and develop methods to …
News Release
NIH is launching a program, Molecular Phenotypes of Null Alleles in Cells (MorPhiC), to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.
… by the program will use versions of genes that do not make functional proteins, called null alleles. In the absence of making its functional protein, a given gene’s function can be more … of human genes. “MorPhiC is meant to add another layer of functional information between the gene knock-out at the DNA …
Staff
Dr. Stephanie Morris is a program director in NHGRI's Division of Genome Sciences.
… on high-throughput genomic technology development and functional genomics. She also oversees NHGRI’s Genome … and extends to interests in technology development and functional genomics. Dr. Morris received a B.A. in biology … development, functional genomics, The Encyclopedia of DNA Elements (ENCODE) Project, Impact of Genomic Variation on …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… and the field of genomics. … The Encyclopedia of DNA Elements (ENCODE) project is an international collaboration … ENCODE’s public research consortium aims to identify all functional elements in the human and mouse genomes. The … 3 reveal the most extensive catalog to date of candidate functional elements that may regulate the genes in the human …
News Release
ENCODE program directors in the Division of Genome Sciences turned to Reddit to answer questions from the Reddit community.
… Human Genome Research Institute's ENCyclopedia Of DNA Elements (ENCODE) Project has spent 13 years building a catalog of all the functional elements in the human genome sequence , and making … … ENCyclopedia Of DNA Elements Project, ENCODE, catalog of functional elements in the human genome sequence, dark matter …
Staff
Dr. Elise Feingold is a scientific program manager in NHGRI's Division of Genome Sciences.
… director focused on gene discovery, gene expression and functional genomics. Since 2019, Dr. Feingold has served as … Dr. Feingold initiated and led the Encyclopedia of DNA Elements (ENCODE) project, which aimed to generate a comprehensive catalog of functional DNA elements within the human and mouse genomes. …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… Medicine, NHGRI; Andrea Beckel-Mitchener, Ph.D., chief, Functional Neurogenomics Program, Division of Neuroscience … grasp wider role for genetic variation in regulatory elements of genome … Researchers find that more than 80 …