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Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… Gene Environment Interaction … Gene environment interaction is an influence on the … … Genes, Environmental Factors, Genetics, DNA … Gene–environment interaction refers to the interplay of genes (and, more broadly, genome function) and the physical and social environment. These …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… and investigate the health consequences of their genes and gene variants. … Reversing a Long-Standing Paradigm To … them to recall genotyped people and examine the genes and gene variants' influence on their phenotypes, an individual's … of Health. The NHGRI Extramural Research Program supports grants for research, and training and career development at …
Educational Resources
A gene pool is the total genetic diversity found within a population or a species.
… Gene Pool … A gene pool is the total genetic diversity found within a … Diversity, Genes, Extinction, Population Genetics … A gene pool refers to the combination of all the genes … present in a reproducing population or species. A large gene pool has extensive genomic diversity and is better able …
News Release
The newly launched Impact of Genomic Variation on Function (IGVF) consortium to include 30 U.S. sites.
… Ph.D. … The newly launched Impact of Genomic Variation on Function (IGVF) consortium to include 30 U.S. sites. … The … over five years to the Impact of Genomic Variation on Function (IGVF) consortium, initiated and funded by NIH’s … to understand how genomic variation alters human genome function, and how such variation influences human health and …
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… of Cardiovascular Disease in Africans Americans Study (GENE-FORECAST®) study is developing a community-based cohort … ancestry-related genomic variation in African-Americans. … GENE-FORECAST® will test the working hypothesis that … pressure), laboratory tests (e.g. lipid levels, kidney function), social determinants profiles (e.g. socioeconomic …
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… Tumor Suppressor Gene … A tumor suppressor gene directs the production of a protein that is part of the … the protein it encodes is not produced or does not function properly, and as a result, uncontrolled cell …
Educational Resources
Gene mapping is the process of establishing the locations of genes on the chromosomes.
… Gene Mapping … Gene mapping is the process of establishing the locations of … Analysis, Genome Sequencing, DNA Sequencing, Chromosomes … Gene mapping refers to the process of determining the … on chromosomes. Today, the most efficient approach for gene mapping involves sequencing a genome and then using …
About NHGRI
NHGRI's Initial Review Group provides first-level peer review of grant applications.
… (PHS) Act, as amended (42 U.S.C. 241), to support through grants, cooperative agreements, and contracts, research … for the formation and use of advisory committees. Function The Initial Review Group shall advise the Director, … and shall be provided information on its name, membership, function, and estimated frequency of meetings. The Chairs of …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
… Gene Amplification … Gene amplification is an increase in the number of copies of a gene sequence. … DNA Sequence, Cancer, PCR, Polymerase Chain …
News Release
Two grants will support studies on genomic literacy among Africans relating to research conducted in Africa by African investigators.
… Steven Benowitz … Two grants totaling more than $300,000 will support studies on … in Africa by African investigators. The three-year grants are part of the Human Heredity and Health in Africa … a project to determine Ethiopians' understanding of gene-environment interactions, with a goal of also increasing …