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Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Genome editing is a method that lets scientists change the DNA of … about 85 percent of their genes! By changing a single gene or multiple genes in a mouse, scientists can observe how … genomic basis of deafness. … Scientists are developing gene therapies - treatments involving genome editing - to …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
… the conversation about the science and ethics of genome editing has grown louder due to faster, cheaper, and more … will aid the development of new treatments, including gene therapy . … Scientists have had the knowledge and … fraction of time and price. … [1] Capecchi, M. R. (2005). Gene targeting in mice: functional analysis of the mammalian …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… runners-up include three relevant to genomics: " pinpoint gene editing ," " a cancer drug's broad swipe ," and " gene therapy triumph ." Nature's list of Science Events …
News Release
NHGRI hosted a CRISPR "Ask Me Anything" with Jennifer Doudna, Ph.D., reaching 10.5 million people worldwide.
… there to tackle some of the ethics questions related to gene editing. Here, we recap the event (or you can check out … proteins in human cells is an important finding. When gene therapies reached clinical trials in the late 1990's, …
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… time, we have developed powerful new technologies for editing a human (or any) genomes? We may not yet have jet … virus to start replicating again. As scientists working on gene therapy for many years have found, there are also … new mosquitoes could be malaria-free. This is called a " gene drive " and it has quickly become controversial. For the …
Outreach
The USA Science and Engineering Festival is an opportunity to take part in hands-on genetics and genomics activities.
… Tree . The CRISPR Corner Are you familiar with the term “gene editing”? Gene editing is a hot topic of discussion and has many …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in … of Genome Research , the researchers reported that the gene-editing technology known as CRISPR/Cas9 is six times more …
News Release
NHGRI researchers asked patients, parents and physicians in the sickle cell disease community (SCD) what they wanted and needed to know about genome editing to make informed decisions about participating in genome-editing clinical trials.
… … As public interest and expanded research in human genome editing grows, many questions remain about ethical, legal and … community what they wanted and needed to know about genome editing to make informed decisions about participating in genome-editing clinical trials. Gene-editing treatments, which appear to provide a potential …
Media Advisory
NHGRI hosts a Reddit AMA with Jennifer Doudna, Ph.D., and her research group.
… her research, her new, NHGRI-funded Center for Genome Editing and Recording, and the CEGS program. The CEGS program … focus on refining technologies, such as the CRISPR-Cas9 gene-editing system, that alter, detect, and record the sequence …
News Release
The U.S. National Institutes of Health (NIH) has long invested in basic genetics and genomics research, clinical trials, as well as translational medicine and social science studies, to advance our understanding of this widespread illness to help develop effective therapies.
… the U.S. Food and Drug Administration (FDA) approved two gene therapies for the treatment of sickle cell disease in … One of the new sickle cell treatments uses the CRISPR gene-editing system, a first for humans in the U.S. NIH …