Search Results
Policies and Guidance
Broad data sharing promotes maximum public benefit from federally funded genomics research. NHGRI supports the broadest appropriate genomic data sharing with timely data release through widely accessible data repositories. These repositories may be open access (unrestricted) or, if more appropriate, controlled access.
… molecular data produced by array-based technologies or high-throughput sequencing technologies. Data pertinent to the …
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… research. Dr. Shawn Burgess' lab at NHGRI has developed a high-throughput pipeline that can create multiple, simultaneous …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… the genome and epigenome. These platforms will enable high-precision engineering of both the nuclear and … these technologies will usher in a new era of safer, high precision and multiplexed genome and epigenome editing. … gone largely unfulfilled. What is needed are facile, high-throughput methods for generating libraries of human cells …
Staff
William J. Pavan, Ph.D. is the chief of NHGRI's Genetic Disease Research Branch.
… occupied the forefront of research innovation by using high-risk screens to identify major modifiers of primary … to identify candidate therapeutic compounds via high-throughput screens, its Therapeutics for Rare and Neglected … in establishment of a natural history study to identify screening criteria and biomarkers for use in gauging …
Staff
Barbara Thomas is a scientific review officer for the Center for Inherited Disease Research (CIDR).
… (CIDR) , a trans-NIH program that provides access to high throughput genotyping and next-generation sequencing services … and decision making through the CIDR Board of Governors, high-level oversight of project management, and data sharing …
Research Funding
The Multi-Omics for Health and Disease Consortium aims to advance the application of multi-omic technologies to study health and disease in ancestrally diverse populations.
…  one or two ‘Omics Production Centers that will utilize high-throughput molecular assays to produce: genomic, epigenomic, …
Staff
Dr. Stephanie Morris is a program director in NHGRI's Division of Genome Sciences.
… in 2019. She manages a portfolio of grants focused on high-throughput genomic technology development and functional …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… recombination is that it is inaccurate and has a high rate of error when the injected DNA fragments insert … J., Xu, L. S., Gallardo, V., . . . Burgess, S. M. (2015). High-throughput gene targeting and phenotyping in zebrafish using …
News Release
Micro-sized technologies are among the approaches researchers will use to develop high quality, low cost DNA sequencing technology.
… - are among the approaches researchers will use to develop high quality, low cost DNA sequencing technology through new … remain in terms of containing costs and achieving a high quality of DNA sequencing data." This group of awards is … methods with biological nanopores to enable high-throughput sequencing. The latter refers to a very high rate …
News Release
NHGRI hosted two Pathway to Independance awardees and supported 18 additional investigators at institutions nationwide.
… Ph.D., Rutgers University, New Brunswick, New Jersey, High-Throughput Mobile Element Genotyping Using Next-Generation …