Search Results
Staff
Dr. Sergey Koren is an associate Investigator in the Genome Informatics Section of the Center for Genomics and Data Science Research.
… Koren researches algorithms for the efficient analysis of large-scale genomic datasets with a focus on genome … S*, Chin CS, Drake JP, Landolin JM, et al. Assembling large genomes with single-molecule sequencing and … … Sergey Koren, Associate Investigator, bioinformatics, large-scale genomic datasets, genome assembly, complete …
News Release
NHGRI appointed Carolyn Hutter, Ph.D., director of the Division of Genome Sciences, which researches human genome function in health and disease.
… comes to the position with extensive experience leading large-scale genomics research programs. Most recently, she … TCGA and other programs. "Working as a program director on large-scale projects taught me the value and rewards that … disease. ​ … Carolyn Hutter, Division of Genome Sciences, large-scale genomics research, The Cancer Genome Atlas, TCGA, …
About Genomics
An interactive timeline listing key moments from the history of the project.
… uses sequence-tagged sites as the landmarks to help order large segments of DNA. The map in 1995 is a significant … within 24 hours of being generated by federally funded large-scale human sequencing centers. The "Bermuda … as finished sequence for studying DNA features that span large regions or require high sequence accuracy over long …
The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
… of genome sequence to public databases weekly, as large-scale DNA sequencing had advanced substantially. At … it became clear that having the local capacity to generate large amounts of DNA sequence data in support of genomics … the present, NISC became a well-respected and highly used large-scale DNA sequencing center that exemplifies the …
News Release
Researchers, clinicians, and computational biologists meet to consider future opportunities for NHGRI's Genome Sequencing Program.
… by 20 percent and split into four major components: the Large-Scale Sequencing and Analysis Centers (LSAC) program; … include: What are the key scientific opportunities for large-scale genomics efforts - in both genome sequencing and … … Genome Sequencing Program (GSP), GSP planning workshops, Large-Scale Sequencing and Analysis Centers, LSAC, Centers …
Event
The Excellence in Clinical Research Seminar Series is designed to facilitate clinical research in the rare disease space with a focus on aspects of regulatory medicine and clinical trials in Mendelian disorders.
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… not last long inside cells.  By injecting cells with a synthetic mRNA that encodes a viral spike protein, an mRNA … alter DNA. Your cells constantly make their own mRNA. The synthetic mRNA in the vaccine acts like any other mRNA that … safe and effective. Two mRNA vaccines have been tested in large-scale clinical trials that included elderly and …
Event
The Advances in Genomic Technology Development (AGTD) 2023 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) in-person and virtually from Tuesday, June 6, until Thursday, June 8, at The Sanford Consortium for Regenerative Medicine, La Jolla, CA.
… system Steven Brueck, Ph.D. Armonica Technologies Synthetic Nucleic Acid Synthesis Technology Session … Kim, Ph.D. Ohio State University 2:00 p.m. Progress toward large-scale de novo direct RNA sequencing using mass … challenges faced with advanced sequencing, genomic, and synthetic nucleic acid technologies and to promote …
AnVIL
The Data Use Oversight System (DUOS) is a semi-automated study registration and DAR management service informed by the GA4GH DUO standard, which enables the secondary use of human genomics and other controlled-access data in compliance with the informed consent of a study’s participants.
Research Funding
A scalable and interoperable resource that leverages cloud-based infrastructure for genomic data access, sharing and computing.​
…  AnVIL facilitates integration and computing on and across large datasets generated by NHGRI programs, as well as … advance for storing, accessing, sharing and computing on large genomic datasets  View: A Summary of Accomplishments … projects relevant to NHGRI’s mission using AnVIL for large-scale data analysis with cloud computing credits. … …