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The Genomics Landscape
In the July 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., emphasizes the importance of the Technology Transfer Office and its mission to manage all the legal negotiations that help to protect federally funded research from being unduly exploited, while also giving that research avenues to reach patients through the commercialization of promising advances.
… work, NHGRI intramural researchers must responsibly share large-scale genomic data with the broader research community. The … Claire joined the NHGRI TTO in 1999. The office oversees a large range of activities that involve the exchange and …
Staff
Dr. Wilson is the co-chief of and senior investigator in NHGRI's Computational and Statistical Genomics Branch.
… of the statistical properties of newly developed methods of genetic analysis for quantitative traits. … The … for sequence variants (tiled regression). In addition, the large and small sample statistical properties of these tests … (millions), e.g. high density SNP panels, and/or large-scale sequencing producing large numbers of rare sequence …
News Release
NHGRI convened geneticists, biologists, clinicians, bioinformatics specialists and more to provide expert advice on the future of its Genome Sequencing Program.
… into the clinic. In addition to the long-established Large-Scale Sequencing and Analysis Center (LSAC) program, the GSP … This means supporting research into new DNA sequencing methods and data analysis techniques and solving difficult …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… These datasets are also used to develop computational methods. The GTEx Consortium consists of over 200 … analyses on them there lowers the barrier to performing large-scale computational research by eliminating the need to …
Fact Sheet
Genomic variation accounts for some of the differences among people, including important aspects of their health and susceptibility to diseases.
… in human genomes, ranging from small differences to large differences.  A very small subset of genomic variants … of new experimental technologies and data-analysis methods. Such advances are readily applicable to ongoing … of nucleotides to larger chromosomal regions. These large-scale genomic differences are called structural variants and …
News Release
Researchers with support from NIH will conduct research into the genetic underpinnings of Alzheimer's disease.
… for using innovative new technologies and computational methods for the analysis. The scientists also will seek … the disorder. They also will study genomic data from 111 large families, a portion of which are of Caribbean Hispanic … goals, the grantees will collaborate with the NHGRI Large-Scale Sequencing and Analysis Centers program, an …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… and African sleeping sickness . "There is a great need for large-scale genetic investigations of diverse groups of people …
Staff
Dr. Leslie Biesecker is a clinical and molecular geneticist in and the chief of NHGRI's Center for Precision Health Research.
… second major area of research is a highly collaborative large-scale medical sequencing project, which aims to develop and … variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance …
Funding Opportunities
Funding Opportunities for Investigator-Initiated Research in Computational Genomics and Data Science
The Computational Genomics and Data Science Program Announcements (PARs) invite applications for investigator-initiated research efforts fostering innovation in computational genomics, data science, statistics, bioinformatics, and data visualization and exploration.
… INSTITUTE Modeling Functional Elements using CRISPR Screening HG010753 QUINLAN, AARON R UNIVERSITY OF UTAH … SHEFFIELD, NATHAN UNIVERSITY OF VIRGINIA Novel methods for large-scale genomic interval comparison HG012558 PARK, PETER J …
Jobs at NHGRI
A postdoctoral training position is currently available in the Computational and Statistical Genomics Branch (CSGB) of the National Human Genome Research Institute (NHGRI).
… and apply bioinformatic approaches to these and other large-scale genomic data sets, focusing on the evolution of … skills and experience in the application of computational methods to genomic data are highly desirable. Applicants must …