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Fact Sheets
Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment.
… DNA into a molecule called messenger ribonucleic acid (mRNA). The mRNA travels out of the nucleus and into the cell's cytoplasm, where the mRNA is read by a tiny molecular machine called a ribosome, …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… Gallagher PG, Bodine DM. Long term expression of g-globin mRNA in mouse erythrocytes from retrovirus vectors containing … Jordan CT, Anderson SM, Cline AP, Bodine DM. The level of mRNA encoding amphotropic retrovirus receptor in mouse and … hematopoietic stem cells contain high levels of mRNA for c-kit, GATA-2, p45NF-E2 and c-myb, and low levels or …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… a synthetic type of DNA generated from messenger RNA, or mRNA, the molecule in the cell that takes information from … and instructs it to make a specific protein. By using mRNA as a template, scientists use enzymatic reactions to …
For Teachers
Lesson plan based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity.
… PROBLEM section: Why can there be more then one possible mRNA sequence for a peptide sequence? #23. A gene is a … #24. The RNA message is sometimes edited. What happens to mRNA when there is no binding region of DNA to match? What is …
Staff
Dr. Douglas Stewart is an associate investigator in NHGRI's Center for Precision Health Research.
… R, Strauss, JF. Increased transcription and increased mRNA stability contribute to increased GATA6 mRNA abundance in PCOS theca cells. Journal of Clinical …
The Genomics Landscape
In the March 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the new fact sheets produced by the institute's Communications and Public Liaison Branch.
… such as COVID-19 vaccine production , PCR testing , and mRNA vaccines . These and other fact sheets include graphical …
News Release
Jeffery Schloss, Ph.D., founding director of the Division of Genome Sciences, is embarking on a new journey: retirement.
… cell movement and the factors that determine how much mRNA is made. He envisioned spending his years conducting …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… either by genes in the Ensembl database, or by human mRNA best BLAT (BLAST-like alignment tool) alignments in the … and which did not correspond to Ensembl genes, GenBank mRNA BLASTZ alignments, Fgenesh++ gene predictions, TwinScan …
News Release
NIH researchers have developed a breath test that measures how well patients with methylmalonic acidemia (MMA) respond to receiving liver or combined liver and kidney transplantation.
… increase in carbon 13 propionate oxidation after gene, mRNA or genome editing therapies,” Venditti said. “This way, …
Policies and Guidance
Frequently Asked Questions regarding the Update to NIH Management of Genomic Summary Results Access.
… traits (e.g., height), or molecular traits (e.g., mRNA or protein expression levels). Examples of these kinds …