Search Results
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… are influenced by how one or more genes interact in complex ways with environmental factors, such as chemicals in …
Research Funding
The centers define the state-of-the-art study designs and methods to find variants and genes underlying Mendelian disorders.
… knowledge can also lend insight into the common or more complex phenotypes that involve similar genes, pathways, and … and candidate gene approaches. The CMGs aim to make major contributions to the discovery of the genetic basis of …
The Genomics Landscape
In the January 2019 edition of The Genomics Landscape, NHGRI Director Dr. Eric Green honors NIAMS Director, Stephen Katz, M.D., Ph.D.
… and genomics. Later this month, NHGRI is hosting our first major strategic planning workshop, entitled "From Genome to … as NIAMS Director, Steve ably led the Institute and made major research contributions related to numerous important … is needed from both NIH and external sources; (2) one major challenge to genomic medicine implementation is the …
News Release
NHGRI published its “Strategic vision for improving human health at The Forefront of Genomics” in the journal Nature. This vision describes the most compelling research priorities and opportunities in human genomics for the coming decade, signaling a new era in genomics for the Institute and the field.
… … The first area represents a compilation of nine major principles and values that provide a guiding compass … community must improve in the coming decade. Some of the complex genomic issues discussed in the new vision relate to …
Jobs at NHGRI
NHGRI seeks to identify outstanding tenure-track or tenure-eligible investigators for the newly established Center for Genomics and Data Science Research (CGDSR) within the Division of Intramural Research, located in Bethesda, Maryland.
… The National Human Genome Research Institute (NHGRI), a major research component of the National Institutes of Health …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… affect how the body processes drugs, while others play a major role in how a fertilized egg develops into a baby. … will take years of research to identify and understand the complex connections among all the molecules in all biological … the prospect of fighting many enemies. Fortunately, this complex view can be simplified by looking at which biological …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… focuses on a spectrum of disorders from those that have a major public health impact to rare genetic conditions with … impacts the flow of information and support across complex social systems. Health disparities We conduct …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease.
… in finding genetic variations that contribute to common, complex diseases, such as asthma, cancer, diabetes, heart … 2006. The initial studies include bipolar disorder, major depression, kidney disease in type 1 diabetes, … National Institute of General Medical Sciences, also are major contributors to the PharmacoGenetics Research Network. …
News Release
Laura Koehly, Ph.D., has been named chief of NHGRI's Social and Behavioral Research Branch.
… … SBRB research includes a focus on disorders that have major public health impact such as attention deficit … give rise to a variety of explanations. She switched her major and studied statistics while maintaining an interest in …
News Release
NHGRI researchers have generated the largest catalog of genetic variants associated with physical traits for domesticated dog breeds.
… breeds. The sheer number of dog breeds points toward the major role played by genetics in shaping such variation in …